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EPHB2 (48CT12.6.4) Monoclonal Antibody

EPHB2 (48CT12.6.4) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 211
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name4) Monoclonal Antibody, 6, EPHB2 (48CT12
Also known as4) Monoclonal Antibody, 6, EPHB2 (48CT12
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEPHB2
SpecificityThis is a highly specific antibody against EPHB2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number4, 48CT12, 6
Source between amino acids 127~425) was used to produce this monoclonal antibody, Purified His-tagged EPHB2 protein(Fragment
Gene ID number2048
Swiss ProtP29323
Tested Applications FCM, IHC-P, WB
Recommended dilutions FC(1:10~50), IHC-P(1:200), WB(1:1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk, Controls other aspects of development including angiogenesis, Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca, Functions in axon guidance during development, In addition to axon guidance, Involved in the guidance of commissural axons, May function as a tumor suppressor, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses, leading to contact-dependent bidirectional signaling into neighboring cells, palate development and in inner ear development through regulation of endolymph production, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex, Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells
Purification method This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CAPB, Developmentally-regulated Eph-related tyrosine kinase, EK5, ELK-related tyrosine kinase, EPH tyrosine kinase 3, EPH-like kinase 5, EPHB2, EPHT3, EPTH3, ERK, Ephrin type-B receptor 2, Hek5, PCBC, Renal carcinoma antigen NY-REN-47, Tyro5, Tyrosine-protein kinase TYRO5, Tyrosine-protein kinase receptor EPH-3, DRT
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target4) Monoclonal, 6, EPHB2 (48CT12
Short name4) Monoclonal Antibody, 6, EPHB2 (48CT12
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name4) monoclonal (Antibody to), 6, EPHB2 (48CT12
Alternative techniqueantibodies
Identity 3393
Gene EPHB2
Long gene name EPH receptor B2
Synonyms gene DRT ERK EPHT3
Synonyms gene name EphB2
Synonyms Hek5 Tyro5
Locus 1p36, 12
Discovery year 1995-05-09
GenBank acession AF025304
Entrez gene record 2048
Pubmed identfication 1648701
RefSeq identity NM_017449
Classification Sterile alpha motif domain containing Fibronectin type III domain containing EPH receptors
Havana BLAST/BLAT OTTHUMG00000002881
Locus Specific Databases LRG_780

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