Name : Ephrin A1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5941510647
| Long name | Ephrin A1 Antibody |
| Also known as | Ephrin A1 Antibody |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Ephrin A1 |
| Specificity | This is a highly specific antibody against Ephrin A1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 140-182/205 |
| Subcellular location | Cell membrane, Secreted |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ephrin A1 |
| Gene ID number | 2041 |
| Swiss Prot | P21709 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand, May play a role in apoptosis, Plays also a role in angiogenesis and regulates cell proliferation, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC, leading to contact-dependent bidirectional signaling into neighboring cells, Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | EPH tyrosine kinase, EPH tyrosine kinase 1, EPHA1, EPHT, EPHT1, Ephrin type-A receptor 1, Erythropoietin-producing hepatoma receptor, Tyrosine-protein kinase receptor EPH, hEpha1, EPH |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Ephrin A1 |
| Short name | Ephrin A1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Ephrin A1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3221 |
| Gene | EFNA1 |
| Long gene name | ephrin A1 |
| Synonyms gene | TNFAIP4 EPLG1 |
| Synonyms gene name | ephrin-A1 |
| Synonyms | LERK1 ECKLG |
| Locus | 1q22 |
| Discovery year | 1992-10-20 |
| Entrez gene record | 1942 |
| Pubmed identfication | 2233719 8660976 |
| RefSeq identity | NM_004428 |
| Classification | Ephrins |
| Havana BLAST/BLAT | OTTHUMG00000035312 |