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Ephrin A1 Antibody

Ephrin A1 Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameEphrin A1 Antibody
Also known asEphrin A1 Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEphrin A1
SpecificityThis is a highly specific antibody against Ephrin A1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range140-182/205
Subcellular location Cell membrane, Secreted
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ephrin A1
Gene ID number2041
Swiss ProtP21709
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand, May play a role in apoptosis, Plays also a role in angiogenesis and regulates cell proliferation, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC, leading to contact-dependent bidirectional signaling into neighboring cells, Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names EPH tyrosine kinase, EPH tyrosine kinase 1, EPHA1, EPHT, EPHT1, Ephrin type-A receptor 1, Erythropoietin-producing hepatoma receptor, Tyrosine-protein kinase receptor EPH, hEpha1, EPH
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetEphrin A1
Short nameEphrin A1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEphrin A1 (Antibody to)
Alternative techniqueantibodies
Identity 3221
Gene EFNA1
Long gene name ephrin A1
Synonyms gene TNFAIP4 EPLG1
Synonyms gene name ephrin-A1
Synonyms LERK1 ECKLG
Locus 1q22
Discovery year 1992-10-20
Entrez gene record 1942
Pubmed identfication 2233719 8660976
RefSeq identity NM_004428
Classification Ephrins
Havana BLAST/BLAT OTTHUMG00000035312

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