Name : Ephrin A1 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5057803751
| Long name | ALEXA FLUOR 594 Conjugated, Ephrin A1 Antibody |
| Also known as | Anti-Ephrin A1 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Ephrin A1 |
| Specificity | This is a highly specific antibody against Ephrin A1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 140-182/205 |
| Subcellular location | Cell membrane, Secreted |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ephrin A1 |
| Gene ID Number | 2041 |
| Swiss Prot | P21709 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand, May play a role in apoptosis, Plays also a role in angiogenesis and regulates cell proliferation, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC, leading to contact-dependent bidirectional signaling into neighboring cells, Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | LERK1 ECKLG |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | Ephrin A1 |
| Short name | Ephrin A1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, Ephrin A1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3221 |
| Gene | EFNA1 |
| Long gene name | ephrin A1 |
| Synonyms gene | TNFAIP4 EPLG1 |
| Synonyms gene name | ephrin-A1 |
| Locus | 1q22 |
| Discovery year | 1992-10-20 |
| Entrez gene record | 1942 |
| Pubmed identfication | 2233719 8660976 |
| RefSeq identity | NM_004428 |
| Classification | Ephrins |
| Havana BLAST/BLAT | OTTHUMG00000035312 |