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EPOR Antibody

EPOR Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameEPOR Primary Polyclonal Antibody
Also known asEPOR PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEPOR
SpecificityThis is a highly specific antibody against EPOR
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range330-380/508
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EPOR
Gene ID number2057
Swiss ProtP19235
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen EPOR dimerizes triggering the JAK2/STAT5 signaling cascade, In some cell types, Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling, May also activate the LYN tyrosine kinase, Mediates erythropoietin-induced erythroblast proliferation and differentiation, Upon EPO stimulation, can also activate STAT1 and STAT3, Receptor for erythropoietin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names EPOR, Erythropoietin receptor, EPO-R
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetEPOR
Short nameEPOR Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameerythropoietin receptor (Antibody to)
Alternative techniqueantibodies
Alternative to gene target EPO-R, EPOR and IDBG-29281 and ENSG00000187266 and 2057, EPOR and IDBG-643528 and ENSBTAG00000008197 and 281144, Epor and IDBG-142378 and ENSMUSG00000006235 and 13857, Extracellular, identical protein binding, this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004900 and erythropoietin receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007420 and brain development and biological process this GO :0007507 and heart development and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0038162 and erythropoietin-mediated signaling pathway and biological process this GO :0042802 and identical protein binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0046697 and decidualization and biological process, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0004900: erythropoietin receptor activity and also this GO :0005515: protein binding and also this GO :0042802: identical protein binding, this GO :0004900: erythropoietin receptor activity, this GO :0005515: protein binding, this GO :0042802: identical protein binding, erythropoietin receptor
Identity 3416
Gene EPOR
Long gene name erythropoietin receptor
Locus 19p13, 2
Discovery year 1990-05-14
GenBank acession M34986
Entrez gene record 2057
Classification Fibronectin type III domain containing
Havana BLAST/BLAT OTTHUMG00000182027

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