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EPS15 Antibody, ALEXA FLUOR 647

EPS15 Antibody, ALEXA FLUOR 647 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 647 Conjugated, EPS15 Polyclonal Antibody
Also known asAnti-EPS15 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenEPS15
SpecificityThis is a highly specific antibody against EPS15
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EPS15
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Eps15 is capable of binding the amino terminal portion of Crk via a conserved proline-rich domain, Eps8 and Eps15 are proteins, Eps8 has been shown to associate with the EGF receptor despite its lack of a functional SH2 domain, Further characterization suggests the protein has both a PH domain and a SH3 domain, Miscues in RTK signaling pathways can result in cellular transformation and ultimately in cancer, Overexpression of Eps15 in NIH/3T3 cells causes cellular transformation, Overexpression of Eps8 in both fibroblasts and hematopoietic cells results in an increased mitogenic response to EGF, Two novel EGF receptor substrates designated EGF-receptor pathway substrates 8 and 15, characteristic of all Crk binding proteins (5), have been described, implying involvement in the regulation of cell proliferation, or Eps8 and Eps15, respectively that become tyrosine phosphorylated subsequent to EGF stimulation, the functional significance of which are not yet known, Elucidation of the mechanism by which receptor tyrosine kinases (RTKs) modulate cellular physiology in response to stimuli is critical to the understanding of growth regulation
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms AF-1P MLLT5
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the EPS15 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetEPS15
Short nameEPS15 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, EPS15 (Antibody to)
Alternative techniqueantibodies
Identity 3419
Gene EPS15
Long gene name epidermal growth factor receptor pathway substrate 15
Locus 1p32, 3
Discovery year 1994-12-19
GenBank acession BC054006
Entrez gene record 2060
Pubmed identfication 8183552
RefSeq identity NM_001981
Classification EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000008192

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