| Long name | ALEXA FLUOR 594 Conjugated, ERCC1 Polyclonal Antibody |
| Also known as | Anti-ERCC1 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ERCC1 |
| Specificity | This is a highly specific antibody against ERCC1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 175-195/297 |
| Subcellular location | Helical |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ERCC1 |
| Gene ID Number | 2067 |
| Swiss Prot | P07992 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Also required for homology-directed repair (HDR) of DNA double-strand breaks, Participates in the processing of anaphase bridge-generating DNA structures, Responsible, and can result in cytokinesis failure, for the first step in the repair of interstrand cross-links (ICL), in conjunction with SLX4, in conjunction with SLX4, which consist in incompletely processed DNA lesions arising during S or G2 phase, Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | RAD10 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | ERCC1 |
| Short name | ERCC1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, complementation family 1 (includes overlapping antisense sequence) (Antibody to), excision repair cross-complementing rodent repair deficiency |
| Alternative technique | antibodies |
| Alternative to gene target | 3'-to lesion and biological process this GO :0006296 and nucleotide-excision repair, 5'-to lesion and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006310 and DNA recombination and biological process this GO :0006312 and mitotic recombination and biological process this GO :0006949 and syncytium formation and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007281 and germ cell development and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007584 and response to nutrient and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008584 and male this GO nad development and biological process this GO :0009650 and UV protection and biological process this GO :0009744 and response to sucrose stimulus and biological process this GO :0010165 and response to X-ray and biological process this GO :0010259 and multicellular organismal aging and biological process this GO :0017025 and TBP-class protein binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0032205 and negative regulation of telomere maintenance and biological process this GO :0035166 and post-embryonic hemopoiesis and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0036297 and interstrand cross-link repair and biological process this GO :0043566 and structure-specific DNA binding and molecular function this GO :0045190 and isotype switching and biological process this GO :0048468 and cell development and biological process this GO :0048477 and oogenesis and biological process this GO :0048568 and embryonic organ development and biological process this GO :0051276 and chromosome organization and biological process this GO :0090305 and nucleic acid phosphodiester bond hydrolysis and biological process, COFS4 and RAD10 and UV20, DNA damage removal and biological process this GO :0000720 and pyrimidine dimer repair by nucleotide-excision repair and biological process this GO :0000737 and DNA catabolic process, DNA incision, DNA incision, ERCC1 and IDBG-57509 and ENSG00000012061 and 2067, ERCC1 and IDBG-639466 and ENSBTAG00000017355 and 615637, Ercc1 and IDBG-150201 and ENSMUSG00000003549 and 13870, complementation group 1 (includes overlapping antisense sequence), endonucleolytic and biological process this GO :0000784 and nuclear chromosome, nuclei, structure-specific DNA binding, telomeric region and cellular component this GO :0001094 and TFIID-class transcription factor binding and molecular function this GO :0001302 and replicative cell aging and biological process this GO :0003677 and DNA binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003697 and single-stranded DNA binding and molecular function this GO :0004519 and endonuclease activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005669 and transcription factor TFIID complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006281 and DNA repair and biological process this GO :0006283 and transcription-coupled nucleotide-excision repair and biological process this GO :0006289 and nucleotide-excision repair and biological process this GO :0006295 and nucleotide-excision repair, this GO :0000014 and single-stranded DNA endodeoxyribonuclease activity and molecular function this GO :0000109 and nucleotide-excision repair complex and cellular component this GO :0000718 and nucleotide-excision repair, this GO :0000014: single-stranded DNA endodeoxyribonuclease activity, this GO :0000014: single-stranded DNA endodeoxyribonuclease activity and also this GO :0001094: TFIID-class transcription factor binding and also this GO :0003677: DNA binding and also this GO :0003684: damaged DNA binding and also this GO :0003697: single-stranded DNA binding and also this GO :0004519: endonuclease activity and also this GO :0005515: protein binding and also this GO :0008022: protein C-terminus binding and also this GO :0017025: TBP-class protein binding and also this GO :0019904: protein domain specific binding and also this GO :0043566: structure-specific DNA binding, this GO :0001094: TFIID-class transcription factor binding, this GO :0003677: DNA binding, this GO :0003684: damaged DNA binding, this GO :0003697: single-stranded DNA binding, this GO :0004519: endonuclease activity, this GO :0005515: protein binding, this GO :0008022: protein C-terminus binding, this GO :0017025: TBP-class protein binding, this GO :0019904: protein domain specific binding, this GO :0043566: structure-specific DNA binding, excision repair cross-complementing rodent repair deficiency |
| Identity | 3433 |
| Gene | ERCC1 |
| Long gene name | ERCC excision repair 1, endonuclease non-catalytic subunit |
| Synonyms gene name | complementation group 1 (includes overlapping antisense sequence) excision repair cross-complementation group 1 , excision repair cross-complementing rodent repair deficiency |
| Locus | 19q13, 32 |
| Discovery year | 2001-06-22 |
| Entrez gene record | 2067 |
| Pubmed identfication | 6462228 26939044 |
| RefSeq identity | NM_001983 |
| Classification | ERCC excision repair associated |
| Havana BLAST/BLAT | OTTHUMG00000182121 |
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