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ERCC6 Antibody, Cy5 Conjugated

ERCC6 Antibody, Cy5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5 Conjugated, ERCC6 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenERCC6
SpecificityThis is a highly specific antibody against ERCC6
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range240-275/1493
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human ERCC6
Gene ID number2074
Swiss ProtQ03468
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background It is required for transcription-coupled repair complex formation, It recruits the CSA complex (DCX(ERCC8) complex), Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions, thereby modifying the interface between stalled RNA polymerase II and DNA, Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms CSB RAD26 ARMD5
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetERCC6 Conjugated
Short name Conjugated, ERCC6 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name complementation family 6 (Antibody to), cyanine 5 coupled, excision repair cross-complementing rodent repair deficiency
Alternative techniqueantibodies
Alternative to gene target ARMD5 and CKN2 and COFS and COFS1 and CSB and RAD26 and UVSS1, ERCC6 and IDBG-304121 and ENSG00000225830 and 2074, ERCC6 and IDBG-631777 and ENSBTAG00000032527 and 522908, Ercc6 and IDBG-147857 and ENSMUSG00000054051 and 319955, complementation group 6, elongation and biological process this GO :0032786 and positive regulation of DNA-templated transcription, elongation and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0045494 and photoreceptor cell maintenance and biological process this GO :0047485 and protein N-terminus binding and molecular function, nuclei, protein N-terminus binding, this GO :0000303 and response to superoxide and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0004386 and helicase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006281 and DNA repair and biological process this GO :0006283 and transcription-coupled nucleotide-excision repair and biological process this GO :0006284 and base-excision repair and biological process this GO :0006289 and nucleotide-excision repair and biological process this GO :0006290 and pyrimidine dimer repair and biological process this GO :0006362 and transcription elongation from RNA polymerase I promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007256 and activation of JNKK activity and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008023 and transcription elongation factor complex and cellular component this GO :0008094 and DNA-dependent ATPase activity and molecular function this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0009411 and response to UV and biological process this GO :0009636 and response to toxic substance and biological process this GO :0010165 and response to X-ray and biological process this GO :0010224 and response to UV-B and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032784 and regulation of DNA-templated transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0004386: helicase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008022: protein C-terminus binding and also this GO :0008094: DNA-dependent ATPase activity and also this GO :0032403: protein complex binding and also this GO :0047485: protein N-terminus binding, this GO :0003682: chromatin binding, this GO :0004386: helicase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008022: protein C-terminus binding, this GO :0008094: DNA-dependent ATPase activity, this GO :0032403: protein complex binding, this GO :0047485: protein N-terminus binding, excision repair cross-complementing rodent repair deficiency
Identity 3438
Gene ERCC6
Long gene name ERCC excision repair 6, chromatin remodeling factor
Synonyms gene CKN2
Synonyms gene name complementation group 6 excision repair cross-complementation group 6 , excision repair cross-complementing rodent repair deficiency
Synonyms name Cockayne syndrome B protein
Locus 10q11, 23
Discovery year 1989-06-30
GenBank acession L04791
Entrez gene record 2074
Pubmed identfication 1339317 19179336
RefSeq identity NM_000124
Classification ERCC excision repair associated
Havana BLAST/BLAT OTTHUMG00000018195
Locus Specific Databases LRG_465

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