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ERCC8/CSA Antibody, Cy7 Conjugated

ERCC8/CSA Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, ERCC8/CSA Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenERCC8/CSA
SpecificityThis is a highly specific antibody against ERCC8/CSA
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range180-230/396
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human ERCC8/CSA
Gene ID number1161
Swiss ProtQ13216
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair, HMGN1 and TCEA1/TFIIS to a transcription-coupled repair complex which removes RNA polymerase II-blocking lesions from the transcribed strand of active genes, It is required for the recruitment of XAB2, The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair, Substrate-recognition component of the CSA complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms CSA
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetERCC8/CSA Conjugated
Short name Conjugated, ERCC8/CSA Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name complementation family 8/CSA (Antibody to), cyanine 7 coupled, excision repair cross-complementing rodent repair deficiency
Alternative techniqueantibodies
Alternative to gene target CKN1 and CSA and UVSS2, ERCC8 and IDBG-22959 and ENSG00000049167 and 1161, ERCC8 and IDBG-628902 and ENSBTAG00000021606 and 518857, Ercc8 and IDBG-181454 and ENSMUSG00000021694 and 71991, complementation group 8, nuclei, protein complex binding, this GO :0000109 and nucleotide-excision repair complex and cellular component this GO :0000209 and protein polyubiquitination and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0006281 and DNA repair and biological process this GO :0006283 and transcription-coupled nucleotide-excision repair and biological process this GO :0006289 and nucleotide-excision repair and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0009411 and response to UV and biological process this GO :0010165 and response to X-ray and biological process this GO :0016363 and nuclear matrix and cellular component this GO :0031464 and Cul4A-RING E3 ubiquitin ligase complex and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0043234 and protein complex and cellular component this GO :0045739 and positive regulation of DNA repair and biological process this GO :0051865 and protein autoubiquitination and biological process, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0032403: protein complex binding, this GO :0005515: protein binding, this GO :0032403: protein complex binding, excision repair cross-complementing rodent repair deficiency
Identity 3439
Gene ERCC8
Long gene name CSA ubiquitin ligase complex subunit , ERCC excision repair 8
Synonyms gene CKN1
Synonyms gene name Cockayne syndrome 1 (classical) excision repair cross-complementing rodent repair deficiency, complementation group 8 excision repair cross-complementation group 8
Locus 5q12, 1
Discovery year 1995-02-07
GenBank acession U28413
Entrez gene record 1161
Pubmed identfication 8596535
RefSeq identity NM_000082
Classification ERCC excision repair associated WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000097741
Locus Specific Databases LRG_466

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