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Erk1 (33A5) Monoclonal Antibody

Erk1 (33A5) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 362
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameErk1 (33A5) Monoclonal Antibody
Also known asErk1 (33A5) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenErk1
SpecificityThis is a highly specific antibody against Erk1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number33A5
SourceRecombinant human protein purified from E, coli (His-Erk1)
Gene ID number5595
Swiss ProtP27361
Tested ApplicationsWB
Recommended dilutions000), WB (1:2
Cross reactivity Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen About 160 substrates have already been discovered for ERKs, BCL6, BTG2, CASP9, CTTN, DAPK1, Depending on the cellular context, ELK1, ERF, FOS, FRS2 or GRB10), GJA1, HSF4 or SPZ1), However, IER3, MAP2, MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade, MAPT, MCL1 or PPARG), Many of these substrates are localized in the nucleus, Moreover, PXN, SORBS3 or STMN1), The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, The substrates include transcription factors (such as ATF2, They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF, adhesion, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors, and seem to participate in the regulation of transcription upon stimulation, and those are responsible for processes such as translation, as well as in the fragmentation of the Golgi apparatus during mitosis, cytoskeletal elements (such as CANX, cytoskeletal rearrangements, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC), mitosis, mitosis and apoptosis, other substrates are found in the cytosol as well as in other cellular organelles, regulators of apoptosis (such as BAD, regulators of translation (such as EIF4EBP1) and a variety of other signaling-related molecules (like ARHGEF2, survival and differentiation through the regulation of transcription, the MAPK/ERK cascade is also involved in the regulation of the endosomal dynamics, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, translation, Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway
Purification methodAmmonium sulfate precipitation
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ERK-1, ERT2, Extracellular signal-regulated kinase 1, HS44KDAP, HUMKER1A, Insulin-stimulated MAP2 kinase, MAP kinase 3, MAP kinase isoform p44, MAPK 3, MAPK3, Microtubule-associated protein 2 kinase, Mitogen-activated protein kinase 3, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK, ERK1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetErk1 (33A5) Monoclonal
Short nameErk1 (33A5) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative nameErk1 (33A5) monoclonal (Antibody to)
Alternative techniqueantibodies

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