ERK1 + ERK2 Antibody, Biotin Conjugated

ERK1 + ERK2 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, ERK1 + ERK2 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	ERK1 + ERK2
Specificity	This is a highly specific antibody against ERK1 + ERK2
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen_range	330-358/358
Subcellular location	Nucleus, Cytoplasm
Source	KLH conjugated synthetic peptide derived from mouse ERK2
Gene ID number	26413
Swiss Prot	P63085
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	About 160 substrates have already been discovered for ERKs, Depending on the cellular context, However, MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade, Many of these substrates are localized in the nucleus, Moreover, The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF, adhesion, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors, and seem to participate in the regulation of transcription upon stimulation, and those are responsible for processes such as translation, as well as in the fragmentation of the Golgi apparatus during mitosis, cytoskeletal rearrangements, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC), mitosis, mitosis and apoptosis, other substrates are found in the cytosol as well as in other cellular organelles, survival and differentiation through the regulation of transcription, the MAPK/ERK cascade is also involved in the regulation of the endosomal dynamics, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, translation, Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	ERK ERK2 p41mapk MAPK2
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	ERK1 + ERK2 Conjugated
Short name	Conjugated, ERK1 + ERK2 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, ERK1 and ERK2 (Antibody to)
Alternative technique	antibodies
Identity	6871
Gene	MAPK1
Long gene name	mitogen-activated protein kinase 1
Synonyms gene	PRKM2 PRKM1
Locus	22q11, 22
Discovery year	1993-11-05
GenBank acession	M84489
Entrez gene record	5594
Classification	Mitogen-activated protein kinases
Havana BLAST/BLAT	OTTHUMG00000030508
Locus Specific Databases	LRG_786

ERK1 + ERK2 Antibody, Biotin Conjugated

ERK1 + ERK2 Antibody, Biotin Conjugated size: 0.1ml 333

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