Filters

ERK5 (Ser731+Thr733) Antibody, ALEXA FLUOR 555

ERK5 (Ser731+Thr733) Antibody, ALEXA FLUOR 555 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, ERK5 (Ser731+Thr733) Polyclonal Antibody
Also known asAnti-ERK5 Ser731+Thr733 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenERK5 Ser731+Thr733
SpecificityThis is a highly specific antibody against ERK5 Ser731+Thr733
ModificationPhosphorylation
Modification SiteSer731+Thr733
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range725-740/816
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human ERK5 around the phosphorylation sites of Ser731+Thr733
Gene ID Number5598
Swiss ProtQ13164
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway, Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction, MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways, May be important for endothelial function and maintenance of blood vessel integrity, May have a role in muscle cell differentiation, Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression, The upstream activator of MAPK7 is the MAPK kinase MAP2K5, Upon activation, differentiation and cell survival, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C, Plays a role in various cellular processes such as proliferation
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms BMK1 ERK5
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetERK5 (Ser731+Thr733)
Short nameERK5 (Ser731+Thr733) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, ERK5 (Ser731+Thr733) (Antibody to)
Alternative techniqueantibodies
Identity 6880
Gene MAPK7
Long gene name mitogen-activated protein kinase 7
Synonyms gene PRKM7
Synonyms name BMK1 kinase extracellular-signal-regulated kinase 5
Locus 17p11, 2
Discovery year 1998-04-28
GenBank acession U25278
Entrez gene record 5598
Pubmed identfication 10072598 7759517
RefSeq identity NM_139033
Classification Mitogen-activated protein kinases
Havana BLAST/BLAT OTTHUMG00000059587

Similar products

Subscribe to our Newsletter