Name : ERK5 (Thr219 + Tyr221) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN3006545940
| Long name | ERK5 (Thr219 + Tyr221) Antibody |
| Also known as | ERK5 (Thr219 + Tyr221) Antibody |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ERK5 Thr219 + Tyr221 |
| Specificity | This is a highly specific antibody against ERK5 Thr219 + Tyr221 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Thr219 + Tyr221 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human ERK5 around the phosphorylation site of Thr219 + Tyr221 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported, In response to extracelluar signals, It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, Jul 2008], MAP kinases act as an integration point for multiple biochemical signals, This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5), [provided by RefSeq, and G protein-coupled receptors, and activating different transcription factors, and are involved in a wide variety of cellular processes such as proliferation, differentiation, this kinase translocates to cell nucleus, transcription regulation and development, where it regulates gene expression by phosphorylating, The protein encoded by this gene is a member of the MAP kinase family |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | BMK 1, BMK 1 kinase, BMK-1, BMK1, BMK1 Kinase, Big MAP kinase 1, EC 2, ERK 4, ERK 5, ERK-5, ERK4, ERK5, ERK5 phospho Thr219 + Tyr221, Extracellular Signal Regulated Kinase 5, Extracellular signal-regulated kinase 5, MAP kinase 7, MAPK 7, MAPK7, MK07_HUMAN, Mitogen Activated Protein Kinase 7, Mitogen-activated protein kinase 7, 7, 11, 24, ERK5 phospho Thr219 + Tyr221 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ERK5 (Thr219 + Tyr221) |
| Short name | ERK5 (Thr219 + Tyr221) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | ERK5 (Thr219 and Tyr221) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6880 |
| Gene | MAPK7 |
| Long gene name | mitogen-activated protein kinase 7 |
| Synonyms gene | PRKM7 |
| Synonyms | BMK1 ERK5 |
| Synonyms name | BMK1 kinase extracellular-signal-regulated kinase 5 |
| Locus | 17p11, 2 |
| Discovery year | 1998-04-28 |
| GenBank acession | U25278 |
| Entrez gene record | 5598 |
| Pubmed identfication | 10072598 7759517 |
| RefSeq identity | NM_139033 |
| Classification | Mitogen-activated protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000059587 |