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Estrogen Receptor alpha (Y537) Antibody, ALEXA FLUOR 555

Estrogen Receptor alpha (Y537) Antibody, ALEXA FLUOR 555 size: 100ul 350

Price 350
Size 100ul
Long name ALEXA FLUOR 555 Conjugated, Estrogen Receptor alpha (Y537) Antibody
Also known asAnti-Estrogen Receptor alpha Tyr537 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenEstrogen Receptor alpha Tyr537
SpecificityThis is a highly specific antibody against Estrogen Receptor alpha Tyr537
ModificationPhosphorylation
Modification SiteTyr537
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human ER alpha around the phosphorylation site of Tyr537
Gene ID Number2099
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen ER Alpha and ER Beta, ER Alpha and ER Beta have been shown to be differentially activated by various ligands, In most cells, The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), The carboxy terminal region of the estrgen receptor contains the ligand binding domain, The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes, Two forms of estrogen receptor have been identified, and the DNA binding domain is centrally located, hPR-B functions as a transcriptional activator of progesterone-responsive gene, the amino terminus serves as the transactivation domain, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors, which arise from alternative splicing, Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms Atherosclerosis, DKFZp686N23123, ER, ER Alpha, ER alpha Tyr537, ER alpha Y537, ER alpha Y537, ER-alpha, ER[a], ERalpha, ESR, ESR1, ESR1_HUMAN, ESR2, ESRA, Era, Estr, Estradiol Receptor-alpha, Estradiol receptor, Estrogen Receptor 1, Estrogen Receptor alpha Tyr537, Estrogen Receptor alpha Y537, Estrogen receptor 1 alpha, Estrogen receptor alpha, Estrogen resistance, HDL cholesterol, Myocardial infarction, NR3A1, Nuclear receptor subfamily 3 group A member 1, OTTHUMP00000017718, OTTHUMP00000017719, RNESTROR, augmented response of, included, included, included, included, p-ER alpha Tyr537, p-ER alpha Y537, susceptibility to, susceptibility to, to hormone replacement, ER alpha Tyr537
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetEstrogen Receptor alpha (Y537)
Short nameEstrogen Receptor alpha (Y537) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, Estrogen Receptor a (Y537) (Antibody to)
Alternative techniqueantibodies

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