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Estrogen Receptor alpha (Y537) Antibody, FITC Conjugated

Estrogen Receptor alpha (Y537) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, Estrogen Receptor alpha (Y537) Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenEstrogen Receptor alpha Tyr537
SpecificityThis is a highly specific antibody against Estrogen Receptor alpha Tyr537
ModificationPhosphorylation
Modification siteTyr537
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human ER alpha around the phosphorylation site of Tyr537
Gene ID number2099
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ER Alpha and ER Beta, ER Alpha and ER Beta have been shown to be differentially activated by various ligands, In most cells, The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), The carboxy terminal region of the estrgen receptor contains the ligand binding domain, The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes, Two forms of estrogen receptor have been identified, and the DNA binding domain is centrally located, hPR-B functions as a transcriptional activator of progesterone-responsive gene, the amino terminus serves as the transactivation domain, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors, which arise from alternative splicing, Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms Atherosclerosis, DKFZp686N23123, ER, ER Alpha, ER alpha Tyr537, ER alpha Y537, ER alpha Y537, ER-alpha, ER[a], ERalpha, ESR, ESR1, ESR1_HUMAN, ESR2, ESRA, Era, Estr, Estradiol Receptor-alpha, Estradiol receptor, Estrogen Receptor 1, Estrogen Receptor alpha Tyr537, Estrogen Receptor alpha Y537, Estrogen receptor 1 alpha, Estrogen receptor alpha, Estrogen resistance, HDL cholesterol, Myocardial infarction, NR3A1, Nuclear receptor subfamily 3 group A member 1, OTTHUMP00000017718, OTTHUMP00000017719, RNESTROR, augmented response of, included, included, included, included, p-ER alpha Tyr537, p-ER alpha Y537, susceptibility to, susceptibility to, to hormone replacement, ER alpha Tyr537
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetEstrogen Receptor alpha (Y537) Conjugated
Short name FITC Conjugated, Estrogen Receptor alpha (Y537) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, Estrogen Receptor a (Y537) (Antibody to)
Alternative techniqueantibodies

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