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Estrogen Receptor Antibody (beta)

Estrogen Receptor Antibody (beta) size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenEstrogen Receptor (beta)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the Estrogen Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis Estrogen Receptor antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q92731
PurityAntigen affinity
Description 100% of mixed growth hormone /prolactin tumors, 80% of somatotroph tumors, ER<, ER<, Estrogen receptor beta is expressed in human thymus, Gene expression was not limited to ERa-positive tumor subtypes, It is expressed in multiple tissues, The DNA-binding domain of ER<, This gene is mapped to 14q and comprises 8 exons spanning approximately 40 kb, and 29% of gonadotroph tumors, and 60% of corticotroph tumors, and has an overlapping but nonidentical tissue distribution, and its splice variants in 60% of prolactinomas, and testis, and the ligand-binding domain shows 58% conserved residues, and was also found in 100% of null cell tumors, however, including developing spermatids of the testis and in ovarian granulosa cells, is 96% conserved compared to ER<, is a member of the superfamily of nuclear receptors which can transduce extracellular signals into transcriptional responses, is homologous to the previously identified ER<, mRNA was coexpressed with ER<, ovary, referred to as ESR2 or ER<, spleen, /font>, /font>, /font>, /font>, /font>, /font>, /font>, Estrogen receptor-beta, a<, a<, a<, b<, b<, b<, b<, font face=symbol>, font face=symbol>, font face=symbol>, font face=symbol>, font face=symbol>, font face=symbol>, font face=symbol>
ImmunogenAn amino acid sequence from the N-terminus of human Estrogen Receptor beta (HGSIYIPSSYVDSHHEYPAMTFYS) was used as the immunogen for this Estrogen Receptor antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Estrogen Receptor antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetEstrogen Receptor (beta)
Short nameEstrogen Receptor Antibody (beta)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEstrogen Receptor (Antibody to) (b)
Alternative techniqueantibodies

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