Name : Estrogen Receptor Antibody (beta)
Supplier : NJS POLY
Price :389
SKU : GEN2650343431
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Estrogen Receptor (beta) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | 5-1ug/ml, Western blot: 0 |
| Notes | Titration of the Estrogen Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This Estrogen Receptor antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q92731 |
| Purity | Antigen affinity |
| Description | 100% of mixed growth hormone /prolactin tumors, 80% of somatotroph tumors, ER<, ER<, Estrogen receptor beta is expressed in human thymus, Gene expression was not limited to ERa-positive tumor subtypes, It is expressed in multiple tissues, The DNA-binding domain of ER<, This gene is mapped to 14q and comprises 8 exons spanning approximately 40 kb, and 29% of gonadotroph tumors, and 60% of corticotroph tumors, and has an overlapping but nonidentical tissue distribution, and its splice variants in 60% of prolactinomas, and testis, and the ligand-binding domain shows 58% conserved residues, and was also found in 100% of null cell tumors, however, including developing spermatids of the testis and in ovarian granulosa cells, is 96% conserved compared to ER<, is a member of the superfamily of nuclear receptors which can transduce extracellular signals into transcriptional responses, is homologous to the previously identified ER<, mRNA was coexpressed with ER<, ovary, referred to as ESR2 or ER<, spleen, /font>, /font>, /font>, /font>, /font>, /font>, /font>, Estrogen receptor-beta, a<, a<, a<, b<, b<, b<, b<, font face=symbol>, font face=symbol>, font face=symbol>, font face=symbol>, font face=symbol>, font face=symbol>, font face=symbol> |
| Immunogen | An amino acid sequence from the N-terminus of human Estrogen Receptor beta (HGSIYIPSSYVDSHHEYPAMTFYS) was used as the immunogen for this Estrogen Receptor antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Estrogen Receptor antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Estrogen Receptor (beta) |
| Short name | Estrogen Receptor Antibody (beta) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Estrogen Receptor (Antibody to) (b) |
| Alternative technique | antibodies |