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Estrogen receptor beta Antibody

Estrogen receptor beta Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameEstrogen receptor beta Antibody
Also known asEstrogen receptor beta Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEstrogen receptor beta
SpecificityThis is a highly specific antibody against Estrogen receptor beta
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range220-270/530
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ER-beta
Gene ID number2100
Swiss ProtQ92731
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binds estrogens with an affinity similar to that of ESR1, DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual, Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner, Nuclear hormone receptor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ER-BETA, ESR-BETA, ESR2, ESRB, ESTRB, Estrogen receptor beta, NR3A2, Nuclear receptor subfamily 3 group A member 2, Erb
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene targetEstrogen receptor beta
Short nameEstrogen receptor beta Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEstrogen receptor b (Antibody to)
Alternative techniqueantibodies
Identity 3468
Gene ESR2
Long gene name estrogen receptor 2
Synonyms gene name estrogen receptor 2 (ER beta)
Synonyms NR3A2 Erb
Synonyms name ER beta
Locus 14q23, 2-q23, 3
Discovery year 1997-01-17
GenBank acession X99101
Entrez gene record 2100
Pubmed identfication 8769313
Classification Nuclear hormone receptors
Havana BLAST/BLAT OTTHUMG00000141306

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