Name : Estrogen receptor beta Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN1427127691
| Long name | ALEXA FLUOR 647 Conjugated, Estrogen receptor beta Antibody |
| Also known as | Anti-Estrogen receptor beta PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Estrogen receptor beta |
| Specificity | This is a highly specific antibody against Estrogen receptor beta |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 220-270/530 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ER-beta |
| Gene ID Number | 2100 |
| Swiss Prot | Q92731 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Binds estrogens with an affinity similar to that of ESR1, DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual, Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner, Nuclear hormone receptor |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | NR3A2 Erb |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Estrogen receptor beta Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Description | 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target | Estrogen receptor beta |
| Short name | Estrogen receptor beta Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, Estrogen receptor b (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3468 |
| Gene | ESR2 |
| Long gene name | estrogen receptor 2 |
| Synonyms gene name | estrogen receptor 2 (ER beta) |
| Synonyms name | ER beta |
| Locus | 14q23, 2-q23, 3 |
| Discovery year | 1997-01-17 |
| GenBank acession | X99101 |
| Entrez gene record | 2100 |
| Pubmed identfication | 8769313 |
| Classification | Nuclear hormone receptors |
| Havana BLAST/BLAT | OTTHUMG00000141306 |