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Estrogen Related Receptor gamma Antibody

Estrogen Related Receptor gamma Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameEstrogen Related Receptor gamma Antibody
Also known asEstrogen Related Receptor gamma Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEstrogen Related Receptor gamma
SpecificityThis is a highly specific antibody against Estrogen Related Receptor gamma
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ESRRG/Estrogen Related Receptor gamma
Gene ID number2104
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen All members of the ESRR family share an almost identical DNA binding domain, It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, Multiple alternatively spliced transcript variants have been identified, The ESRR family is closely related to the estrogen receptor (ER) family, The ESRR members are orphan nuclear receptors, They share target genes, and activate genes controlled by both response elements in the absence of any ligands, and by targeting the same set of genes, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation, co-regulators and promoters, modulates cell proliferation and estrogen signaling in breast cancer, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways, they bind to the estrogen response element and steroidogenic factor 1 response element, which belongs to the nuclear hormone receptor superfamily, which is composed of two C4-type zinc finger motifs, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region, This gene encodes a member of the estrogen receptor-related receptor (ESRR) family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ERR G2, ERR gamma 2, ERR gamma-2, ERR3, ERR3_HUMAN, ERRG 2, ERRG2, ESRRG, Estrogen receptor related protein 3, Estrogen receptor-related protein 3, Estrogen-related receptor gamma, NR3B3, Nuclear receptor subfamily 3 group B member 3, ERR 3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetEstrogen Related Receptor gamma
Short nameEstrogen Receptor gamma Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEstrogen Related Receptor g (Antibody to)
Alternative techniqueantibodies
Identity 3474
Gene ESRRG
Long gene name estrogen related receptor gamma
Synonyms NR3B3
Locus 1q41
Discovery year 1998-02-17
GenBank acession AF058291
Entrez gene record 2104
Pubmed identfication 9676434 10072763
RefSeq identity NM_206595
Classification Nuclear hormone receptors
Havana BLAST/BLAT OTTHUMG00000037025

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