| Long name | ALEXA FLUOR 594 Conjugated, ETS1 associated protein II Antibody |
| Also known as | Anti-ETS1 associated protein II PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ETS1 associated protein II |
| Specificity | This is a highly specific antibody against ETS1 associated protein II |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ETS1 associated protein II/EAPII |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue, Has also 3'-tyrosyl DNA phosphodiesterase activity, Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals, May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation, The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, but less efficiently and much slower than TDP1, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation, giving rise to DNA with a free 5' phosphate, DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ10768 ETS-1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | ETS1 associated protein II |
| Short name | ETS1 associated protein II Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) associated protein II (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006955 and immune response and biological process this GO :0007565 and female pregnancy and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009611 and response to wounding and biological process this GO :0009612 and response to mechanical stimulus and biological process this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0010715 and regulation of extracellular matrix disassembly and biological process this GO :0021854 and hypothalamus development and biological process this GO :0021983 and pituitary gland development and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030578 and PML body organization and biological process this GO :0032355 and response to estradiol and biological process this GO :0034616 and response to laminar fluid shear stress and biological process this GO :0035035 and histone acetyltransferase binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045171 and intercellular bridge and cellular component this GO :0045648 and positive regulation of erythrocyte differentiation and biological process this GO :0045765 and regulation of angiogenesis and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046677 and response to antibiotic and biological process this GO :0048870 and cell motility and biological process this GO :0051272 and positive regulation of cellular component movement and biological process this GO :0060055 and angiogenesis involved in wound healing and biological process this GO :0060206 and estrous cycle phase and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0070555 and response to interleukin-1 and biological process, ETS-1 and EWSR2 and p54, ETS1 and IDBG-642787 and ENSBTAG00000002341 and 540313, ETS1 and IDBG-75897 and ENSG00000134954 and 2113, Ets1 and IDBG-147548 and ENSMUSG00000032035 and 23871, nuclei, sequence-specific DNA binding, this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001666 and response to hypoxia and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006355 and regulation of transcription, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0035035: histone acetyltransferase binding and also this GO :0043565: sequence-specific DNA binding, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0035035: histone acetyltransferase binding, this GO :0043565: sequence-specific DNA binding, v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) |
| Identity | 3488 |
| Gene | ETS1 |
| Long gene name | ETS proto-oncogene 1, transcription factor |
| Synonyms gene | EWSR2 |
| Synonyms gene name | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| Synonyms name | Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1 ets protein |
| Locus | 11q24, 3 |
| Discovery year | 1986-01-01 |
| Entrez gene record | 2113 |
| Pubmed identfication | 1522903 |
| RefSeq identity | NM_005238 |
| Classification | ETS transcription factor family |
| Havana BLAST/BLAT | OTTHUMG00000165799 |
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