Name : EVER2/TMC8 Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN9726661293
| Long name | Cy7 Conjugated, EVER2/TMC8 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | EVER2/TMC8 |
| Specificity | This is a highly specific antibody against EVER2/TMC8 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human EVER2/TMC8 |
| Gene ID number | 147138 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Infection by HPVs lead to persistent wart-like or macular lesions, Localized to the endoplasmic reticulum membrane, Mutations in the genes encoding TMC8 and TMC6, TMC8 is expressed in placenta, TMC8 is thought to form a transmembrane channel-like protein with eight predicted transmembrane domains and three leucine zipper motifs, also known as Epidermodysplasia verruciformis protein 2 (EVER2), an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin, and three named isoforms exist as a result of alternative splicing events, another member of the TMC family, have been shown to cause epidermodysplasia verruciformis (EV), is a 726 amino acid member of the TMC family of proteins, prostate and testis, Transmembrane channel-like protein 8 (TMC8) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | EVIN2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | EVER2/TMC8 Conjugated |
| Short name | Conjugated, EVER2/TMC8 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, EVER2/TMC8 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 20474 |
| Gene | TMC8 |
| Long gene name | transmembrane channel like 8 |
| Synonyms gene | EVER2 |
| Synonyms gene name | epidermodysplasia verruciformis 2 |
| Locus | 17q25, 3 |
| Discovery year | 2003-02-17 |
| GenBank acession | AY057380 |
| Entrez gene record | 147138 |
| Pubmed identfication | 12426567 |
| Classification | Transmembrane channel likes |
| Havana BLAST/BLAT | OTTHUMG00000177436 |
| Locus Specific Databases | TMC8base: Mutation registry for Epidermodysplasia verruciformis (previously known as EVER2base) LRG_119 |