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EXOSC10/PMSCL2 Antibody

EXOSC10/PMSCL2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameEXOSC10/PMSCL2 Primary Polyclonal Antibody
Also known asEXOSC10/PMSCL2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEXOSC10/PMSCL2
SpecificityThis is a highly specific antibody against EXOSC10/PMSCL2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EXOSC10/PMSCL2
Gene ID number5394
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen EXOSC10, EXOSC10 is part of the post-splicing exosome complex and is involved in mRNA surveillance, Localized to both the cytoplasm and the nucleus, PM-Scl, PMSCL2, RRP6, Rrp6p, The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3â, Two isoforms of EXOSC10 exist due to alternative splicing events, against EXOSC10 have been found in patients with scleroderma and/or polymyositis (chronic diseases of the skin and muscle, also known as PMSCL, enonuclease domain, exoribonucleases, is an 885 amino acid protein that contains one HRDC domain and one 3â, mRNA nuclear export and nonsense-mediated decay of mRNAs containing premature stop codons, or PM/Scl-100, p2, p3, p4, region, respectively), some of which are 3â, suggesting that EXOSC10 may be involved in the pathogenesis of these diseases, to 5â, &euro, &euro, &euro, &euro, &euro, &trade, &trade, &trade, &trade, &trade, -5â, The exosome is a multi-subunit complex composed of several highly conserved proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names EXOSX_HUMAN, Exosc10, Exosome component 10, P100 polymyositis scleroderma overlap syndrome associated autoantigen, P100 polymyositis-scleroderma overlap syndrome-associated autoantigen, PM Scl, PM/Scl 100, PM/Scl-100, PMSCL, PMSCL2, Polymyositis/scleroderma autoantigen 100 kDa, Polymyositis/scleroderma autoantigen 2, Polymyositis/scleroderma autoantigen 2 100 kDa, RRP6, Rrp6p, p2, p3, p4, Autoantigen PM/Scl 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetEXOSC10/PMSCL2
Short nameEXOSC10/PMSCL2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEXOSC10/PMSCL2 (Antibody to)
Alternative techniqueantibodies
Identity 9138
Gene EXOSC10
Long gene name exosome component 10
Synonyms gene PMSCL2
Synonyms gene name 100kDa , polymyositis/scleroderma autoantigen 2
Synonyms PM-Scl PM/Scl-100 Rrp6p RRP6 p2 p3 p4
Synonyms name polymyositis/scleroderma autoantigen 2 (100kD)
Locus 1p36, 22
Discovery year 1994-09-19
GenBank acession BC073788
Entrez gene record 5394
Pubmed identfication 1383382 1644924
RefSeq identity NM_001001998
Classification Exosome complex
Havana BLAST/BLAT OTTHUMG00000002123

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