Name : EXOSC10/PMSCL2 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN1765337288
| Long name | ALEXA FLUOR 647 Conjugated, EXOSC10/PMSCL2 Polyclonal Antibody |
| Also known as | Anti-EXOSC10/PMSCL2 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | EXOSC10/PMSCL2 |
| Specificity | This is a highly specific antibody against EXOSC10/PMSCL2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EXOSC10/PMSCL2 |
| Gene ID Number | 5394 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | EXOSC10, EXOSC10 is part of the post-splicing exosome complex and is involved in mRNA surveillance, Localized to both the cytoplasm and the nucleus, PM-Scl, PMSCL2, RRP6, Rrp6p, The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3â, Two isoforms of EXOSC10 exist due to alternative splicing events, against EXOSC10 have been found in patients with scleroderma and/or polymyositis (chronic diseases of the skin and muscle, also known as PMSCL, enonuclease domain, exoribonucleases, is an 885 amino acid protein that contains one HRDC domain and one 3â, mRNA nuclear export and nonsense-mediated decay of mRNAs containing premature stop codons, or PM/Scl-100, p2, p3, p4, region, respectively), some of which are 3â, suggesting that EXOSC10 may be involved in the pathogenesis of these diseases, to 5â, &euro, &euro, &euro, &euro, &euro, &trade, &trade, &trade, &trade, &trade, -5â, The exosome is a multi-subunit complex composed of several highly conserved proteins |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | PM-Scl PM/Scl-100 Rrp6p RRP6 p2 p3 p4 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the EXOSC10/PMSCL2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | EXOSC10/PMSCL2 |
| Short name | EXOSC10/PMSCL2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, EXOSC10/PMSCL2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9138 |
| Gene | EXOSC10 |
| Long gene name | exosome component 10 |
| Synonyms gene | PMSCL2 |
| Synonyms gene name | 100kDa , polymyositis/scleroderma autoantigen 2 |
| Synonyms name | polymyositis/scleroderma autoantigen 2 (100kD) |
| Locus | 1p36, 22 |
| Discovery year | 1994-09-19 |
| GenBank acession | BC073788 |
| Entrez gene record | 5394 |
| Pubmed identfication | 1383382 1644924 |
| RefSeq identity | NM_001001998 |
| Classification | Exosome complex |
| Havana BLAST/BLAT | OTTHUMG00000002123 |