Name : EXOSC10/PMSCL2 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN8598141991
| Long name | Biotin Conjugated, EXOSC10/PMSCL2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | EXOSC10/PMSCL2 |
| Specificity | This is a highly specific antibody against EXOSC10/PMSCL2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human EXOSC10/PMSCL2 |
| Gene ID number | 5394 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | EXOSC10, EXOSC10 is part of the post-splicing exosome complex and is involved in mRNA surveillance, Localized to both the cytoplasm and the nucleus, PM-Scl, PMSCL2, RRP6, Rrp6p, The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3â, Two isoforms of EXOSC10 exist due to alternative splicing events, against EXOSC10 have been found in patients with scleroderma and/or polymyositis (chronic diseases of the skin and muscle, also known as PMSCL, enonuclease domain, exoribonucleases, is an 885 amino acid protein that contains one HRDC domain and one 3â, mRNA nuclear export and nonsense-mediated decay of mRNAs containing premature stop codons, or PM/Scl-100, p2, p3, p4, region, respectively), some of which are 3â, suggesting that EXOSC10 may be involved in the pathogenesis of these diseases, to 5â, &euro, &euro, &euro, &euro, &euro, &trade, &trade, &trade, &trade, &trade, -5â, The exosome is a multi-subunit complex composed of several highly conserved proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | PM-Scl PM/Scl-100 Rrp6p RRP6 p2 p3 p4 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | EXOSC10/PMSCL2 Conjugated |
| Short name | Conjugated, EXOSC10/PMSCL2 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, EXOSC10/PMSCL2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9138 |
| Gene | EXOSC10 |
| Long gene name | exosome component 10 |
| Synonyms gene | PMSCL2 |
| Synonyms gene name | 100kDa , polymyositis/scleroderma autoantigen 2 |
| Synonyms name | polymyositis/scleroderma autoantigen 2 (100kD) |
| Locus | 1p36, 22 |
| Discovery year | 1994-09-19 |
| GenBank acession | BC073788 |
| Entrez gene record | 5394 |
| Pubmed identfication | 1383382 1644924 |
| RefSeq identity | NM_001001998 |
| Classification | Exosome complex |
| Havana BLAST/BLAT | OTTHUMG00000002123 |