Name : Exportin 5 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1658526711
| Long name | Exportin 5 Primary Polyclonal Antibody |
| Also known as | Exportin 5 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Exportin 5 |
| Specificity | This is a highly specific antibody against Exportin 5 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Exportin 5 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | More recently, Research studies have shown disruption of exportin 5 functions in many types of cancers including breast and lung, Study of the miRNA biosynthesis pathway is essential in understanding the process of oncogenesis as global downregulation of miRNAs and the resulting alterations in the expression of tumor suppressor and oncogenic proteins is a common phenotype of cancers cells , family of proteins and functions in tRNA export in a sequence dependent fashion, it has been shown to export pre-miRNA by a RanGTPase-driven process from the nucleus to the cytoplasm, where pre-miRNA accumulates in the nucleus and miRNA maturation is impaired, where pre-miRNA processing occurs to produce mature miRNAs, ², Exportin 5 (XPO5) is a member of the importin Î |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Exp5, Exportin 5, Exportin-5, Exportin5, FLJ14239, FLJ32057, FLJ45606, KIAA1291, Ran binding protein 21, Ran-binding protein 21, Ranbp 21, Ranbp21, XPO5_HUMAN, Xpo 5, xpo5, Exp 5 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Exportin 5 |
| Short name | Exportin 5 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Exportin 5 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17675 |
| Gene | XPO5 |
| Long gene name | exportin 5 |
| Synonyms | KIAA1291 |
| Locus | 6p21, 1 |
| Discovery year | 2003-03-10 |
| GenBank acession | AB033117 |
| Entrez gene record | 57510 |
| Pubmed identfication | 11777942 12426392 |
| RefSeq identity | NM_020750 |
| Classification | Exportins |
| Havana BLAST/BLAT | OTTHUMG00000014742 |