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Factor I heavy chain Antibody, Biotin Conjugated

Factor I heavy chain Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Factor I heavy chain Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFactor I heavy chain
SpecificityThis is a highly specific antibody against Factor I heavy chain
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human Complement factor I heavy chain
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CR1 or MCP are required for C3b cleavage, Complement protein Factor I is a key serine protease that modulates the complement cascade by regulating the levels of C3 convertases, Factor H, Factor I is a serine protease with a high degree of specificity for C3b and C4b, It circulates in plasma as a heavily N-glycosylated heterodimer made up of two disulfide linked chains, It requires protein cofactors for cleavage of these complement proteins, There are three pathways of complement activation: the classical pathway, and C4bp or CR1 are required for C4b cleavage, each carrying three N-linked oligosaccharide chains that may have both structural and functional roles in the interactions with the natural substrate and the cofactor during catalysis, lectin pathway and alternative pathway, The complement pathway is an important host defense system that contributes to both innate and acquired immunity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms , AHUS3, C3B/C4B inactivator, C3BINA, C3b INA, C3b inactivator, CFAI_HUMAN, CFI, Complement component I, Complement control protein factor I, Complement factor I, Complement factor I heavy chain, F1, FI, FactorI, Heavy chain of factor I, I factor, KAF, Konglutinogen activating factor, OTTHUMP00000219728, factor I, Factor I heavy chain
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFactor I heavy chain Conjugated
Short name Conjugated, Factor I heavy chain Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Factor I heavy epitope (Antibody to)
Alternative techniqueantibodies

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