Name : Factor I light chain Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6858613580
| Long name | Factor I light chain Primary Polyclonal Antibody |
| Also known as | Factor I light chain PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Factor I light chain |
| Specificity | This is a highly specific antibody against Factor I light chain |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Factor I Complement factor I light chain |
| Gene ID number | 3426 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | CR1 or MCP are required for C3b cleavage, Complement protein Factor I is a key serine protease that modulates the complement cascade by regulating the levels of C3 convertases, Factor H, Factor I is a serine protease with a high degree of specificity for C3b and C4b, It circulates in plasma as a heavily N-glycosylated heterodimer made up of two disulfide linked chains, It requires protein cofactors for cleavage of these complement proteins, There are three pathways of complement activation: the classical pathway, and C4bp or CR1 are required for C4b cleavage, each carrying three N-linked oligosaccharide chains that may have both structural and functional roles in the interactions with the natural substrate and the cofactor during catalysis, lectin pathway and alternative pathway, The complement pathway is an important host defense system that contributes to both innate and acquired immunity |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | , AHUS3, C3B/C4B inactivator, C3BINA, C3b INA, C3b inactivator, CFAI_HUMAN, CFI, Complement component I, Complement control protein factor I, Complement factor I, Complement factor I light chain, F1, FI, FactorI, I factor, KAF, Konglutinogen activating factor, Light chain of factor I, OTTHUMP00000219728, factor I, Factor I light chain |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Factor I light chain |
| Short name | Factor I light chain Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Factor I light epitope (Antibody to) |
| Alternative technique | antibodies |