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Factor XII heavy chain Antibody

Factor XII heavy chain Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFactor XII heavy chain Antibody
Also known asFactor XII heavy chain Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFactor XII heavy chain
SpecificityThis is a highly specific antibody against Factor XII heavy chain
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Coagulation factor XIIa heavy chain
Gene ID number2161
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged, It activates coagulation factors VII and XI, Jul 2008], On activation, Prekallikrein is cleaved by factor XII to form kallikrein, The active factor XIIa participates in the initiation of blood coagulation, The heavy chain contains two fibronectin-type domains, This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain, [provided by RefSeq, a kringle domain and a proline-rich domain, and the generation of bradykinin and angiotensin, fibrinolysis, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain, two epidermal growth factor (EGF)-like domains, whereas the light chain contains only a catalytic domain, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa, This gene encodes coagulation factor XII which circulates in blood as a zymogen
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Coagulation factor XII, Coagulation factor XIIa heavy chain, Coagulation factor XIIa heavy chain, F12, F12 deficiency, FA12_HUMAN, Factor XII deficiency, Factor XII heavy chain, HAE3, HAEX, HAF, HAF deficiency, Hageman factor, Factor XII
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFactor XII heavy chain
Short nameFactor XII heavy chain Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFactor XII heavy epitope (Antibody to)
Alternative techniqueantibodies

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