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FAIM2 Antibody

FAIM2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFAIM2 Primary Polyclonal Antibody
Also known asFAIM2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFAIM2
SpecificityThis is a highly specific antibody against FAIM2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FAIM2
Gene ID number23017
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Disruption of this process has been implicated in a variety of diseases such as cancer, FAIM2, FAIM2 is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal, FAIM2 is functionally similar to the anti-apoptotic proteins FAIM, FAIM2 is widely distributed, FAIM2 was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway, FLIP and Bcl-xL, In this respect, a seven membrane spanning protein, and removal of damaged cells, but highly expressed in the hippocampus and other neural tissues, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas, tissue homeostasis, Programmed cell death regulates a number of biological processes such as normal organism development
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Fas apoptotic inhibitory molecule 2, LFG, LFG2_HUMAN, Leguard, NGP 35, NGP35, NMP 35, NMP35, Neural membrane protein 35, Protein leguard, TMBIM 2, TMBIM2, Transmembrane BAX inhibitor mot containing 2, Transmembrane BAX inhibitor mot containing protein 2, FAIM 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFAIM2
Short nameFAIM2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name member 6) apoptotic inhibitory molecule 2 (Antibody to), Fas (TNF receptor superfamily
Alternative techniqueantibodies
Alternative to gene target Cell surfaces, FAIM2 and IDBG-32034 and ENSG00000135472 and 23017, FAIM2 and IDBG-632463 and ENSBTAG00000017504 and 509790, Faim2 and IDBG-183291 and ENSMUSG00000023011 and 72393, LFG and LFG2 and NGP35 and NMP35 and TMBIM2, this GO :0002931 and response to ischemia and biological process this GO :0006915 and apoptotic process and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0021549 and cerebellum development and biological process this GO :0021680 and cerebellar Purkinje cell layer development and biological process this GO :0021681 and cerebellar granular layer development and biological process this GO :0021702 and cerebellar Purkinje cell differentiation and biological process this GO :0030054 and cell junction and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045121 and membrane raft and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :2001234 and negative regulation of apoptotic signaling pathway and biological process, Fas apoptotic inhibitory molecule 2
Identity 17067
Gene FAIM2
Long gene name Fas apoptotic inhibitory molecule 2
Synonyms KIAA0950 LFG NMP35 LIFEGUARD TMBIM2 LFG2
Synonyms name transmembrane BAX inhibitor motif containing 2
Locus 12q13, 12
Discovery year 2002-10-08
GenBank acession AB023167
Entrez gene record 23017
Pubmed identfication 10231032 10535980
RefSeq identity NM_012306
Classification Transmembrane BAX inhibitor motif containing
Havana BLAST/BLAT OTTHUMG00000169808

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