Name : FAK(Ser910) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN1645180921
| Long name | FAK(Ser910) Primary Polyclonal Antibody |
| Also known as | FAK(Ser910) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | FAK Ser910 |
| Specificity | This is a highly specific antibody against FAK Ser910 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser910 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human PTK2 around the phosphorylation site of Tyr910 |
| Gene ID number | 5747 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly, Plays a potential role in oncogenic transformations resulting in increased kinase activity, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy, proliferation and apoptosis, Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | FADK, FADK 1, FAK 1, FAK related non kinase polypeptide, FAK1, FAK1_HUMAN, FRNK, Focal adhesion kinase 1, Focal adhesion kinase-related nonkinase, PPP1R71, PTK 2, Protein Tyrosine Kinase Cytoplasmic, Protein phosphatase 1 regulatory subunit 71, Protein tyrosine kinase 2, Protein-tyrosine kinase 2, p-FAK phospho S910, p125FAK, pp125FAK, FAK phospho S910 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FAK(Ser910) |
| Short name | FAK(Ser910) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | FAK(Ser910) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9611 |
| Gene | PTK2 |
| Long gene name | protein tyrosine kinase 2 |
| Synonyms gene name | PTK2 protein tyrosine kinase 2 |
| Synonyms | FAK FADK FAK1 PPP1R71 |
| Synonyms name | protein phosphatase 1, regulatory subunit 71 |
| Locus | 8q24, 3 |
| Discovery year | 1992-10-02 |
| GenBank acession | L13616 |
| Entrez gene record | 5747 |
| Pubmed identfication | 8422239 |
| RefSeq identity | NM_005607 |
| Classification | Protein phosphatase 1 regulatory subunits FERM domain containing |
| Havana BLAST/BLAT | OTTHUMG00000067438 |