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FAK (Tyr397) Antibody

FAK (Tyr397) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFAK (Tyr397) Primary Polyclonal Antibody
Also known asFAK (Tyr397) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFAK Tyr397
Specificity This phosphorylation site is homologous to that of Tyr428 in Mouse and Tyr397 in Rat, This is a highly specific antibody against FAK Tyr397
Modification(s)Phosphorylation
Modification site(s)Tyr397
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range352-402/1052
Subcellular location Cell membrane, Nucleus, Cytoplasm
SourceKLH cunjugated synthetic phosphopeptide derived from human FAK 1 around the phosphorylation site of Tyr397
Gene ID number5747
Swiss ProtQ05397
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix, Dec 2010], Several transcript variants encoding different isoforms have been found for this gene, The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies, [provided by RefSeq, but the full-length natures of only three of them have been determined, This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FADK, FADK 1, FAK1, FRNK, Focal adhesion kinase 1, Focal adhesion kinase-related nonkinase, PPP1R71, PTK2, Protein phosphatase 1 regulatory subunit 71, Protein-tyrosine kinase 2, p125FAK, pp125FAK, FAK
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFAK (Tyr397)
Short nameFAK (Tyr397) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFAK (Tyr397) (Antibody to)
Alternative techniqueantibodies
Identity 9611
Gene PTK2
Long gene name protein tyrosine kinase 2
Synonyms gene name PTK2 protein tyrosine kinase 2
Synonyms FAK FADK FAK1 PPP1R71
Synonyms name protein phosphatase 1, regulatory subunit 71
Locus 8q24, 3
Discovery year 1992-10-02
GenBank acession L13616
Entrez gene record 5747
Pubmed identfication 8422239
RefSeq identity NM_005607
Classification Protein phosphatase 1 regulatory subunits FERM domain containing
Havana BLAST/BLAT OTTHUMG00000067438

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