Name : FAK (Tyr407) Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN5539318112
| Long name | Biotin Conjugated, FAK (Tyr407) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FAK Tyr407 |
| Specificity | This is a highly specific antibody against FAK Tyr407 |
| Modification | Phosphorylation |
| Modification site | Tyr407 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human FAK around the phosphorylation site of Tyr407 |
| Gene ID number | 5747 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, Cell membrane, Cytoplasmic side, Note=Constituent of focal adhesions, Peripheral membrane protein, Plays a potential role in oncogenic transformations resulting in increased kinase activity, [SUBCELLULAR LOCATION] Cell junction, focal adhesion, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy, proliferation and apoptosis, Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | FAK FADK FAK1 PPP1R71 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FAK (Tyr407) Conjugated |
| Short name | Conjugated, FAK (Tyr407) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, FAK (Tyr407) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9611 |
| Gene | PTK2 |
| Long gene name | protein tyrosine kinase 2 |
| Synonyms gene name | PTK2 protein tyrosine kinase 2 |
| Synonyms name | protein phosphatase 1, regulatory subunit 71 |
| Locus | 8q24, 3 |
| Discovery year | 1992-10-02 |
| GenBank acession | L13616 |
| Entrez gene record | 5747 |
| Pubmed identfication | 8422239 |
| RefSeq identity | NM_005607 |
| Classification | Protein phosphatase 1 regulatory subunits FERM domain containing |
| Havana BLAST/BLAT | OTTHUMG00000067438 |