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FANCA Antibody, ALEXA FLUOR 594

FANCA Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, FANCA Polyclonal Antibody
Also known asAnti-FANCA PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFANCA
SpecificityThis is a highly specific antibody against FANCA
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FANCA
Gene ID Number2175
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen At least eight complementation groups (A-G) have been identified and six FA genes (for subtypes A, At the cellular level, C, D2, E, F and G) have been cloned, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents, FANCA, FANCA is mainly expressed in lymphoid tissues, FANCC binding, Phosphorylation of FANC (Fanconi anemia complementation group) proteins is thought to be important for the function of the FA pathway, The FA proteins lack sequence homologies or motifs that could point to a molecular function, The amino-terminal region of the FANCA protein is required for FANCG binding, The cellular accumulation of FA proteins, The human FANCA gene maps to chromosome 16q24, a subunit of the SWI/SNF complex which remodels chromatin structure through a DNA-dependent ATPase activity, also known as FACA and FANCH, associates with the Brm-related gene 1 (BRG1) product, birth defects and chromosomal instability, including FANCA and FANCG, is subject to regulation by TNF alpha signaling, nuclear localization and functional activity of the complex, testis and ovary, 3 and encodes a 1, 455 amino acid protein, Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms FAA FA-H FAH
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetFANCA
Short nameFANCA Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, complementation family A (Antibody to), Fanconi anemia
Alternative techniqueantibodies
Alternative to gene target FA and FA-H and FA1 and FAA and FACA and FAH and FANCH, FANCA and IDBG-48213 and ENSG00000187741 and 2175, FANCA and IDBG-630970 and ENSBTAG00000001906 and, Fanca and IDBG-198733 and ENSMUSG00000032815 and 14087, complementation group A, nuclei, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006281 and DNA repair and biological process this GO :0006461 and protein complex assembly and biological process this GO :0007140 and male meiosis and biological process this GO :0008584 and male this GO nad development and biological process this GO :0008585 and female this GO nad development and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0043240 and Fanconi anaemia nuclear complex and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding, Fanconi anemia
Identity 3582
Gene FANCA
Long gene name Fanconi anemia complementation group A
Synonyms gene FACA FANCH
Locus 16q24, 3
Discovery year 1995-12-22
GenBank acession Z83067
Entrez gene record 2175
Pubmed identfication 7581462 9382107
Classification Fanconi anemia complementation groups
Havana BLAST/BLAT OTTHUMG00000173049
Locus Specific Databases Fanconi Anaemia Mutation Database Fanconi anemia database LRG_495

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