FANCA (Ser1149) Antibody

FANCA (Ser1149) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 281

Size 0.1ml

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Long name	FANCA (Ser1149) Primary Polyclonal Antibody
Also known as	FANCA (Ser1149) PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	FANCA Ser1149
Specificity	This is a highly specific antibody against FANCA Ser1149
Modification(s)	Phosphorylation
Modification site(s)	Ser1149
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic phosphopeptide derived from human FANCA around the phosphorylation site of Ser1149
Gene ID number	2175
Tested Applications	IF(IHC-P), IHC-P, WB
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	At least eight complementation groups (A-G) have been identified and six FA genes (for subtypes A, At the cellular level, C, D2, E, F and G) have been cloned, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents, FANCA, FANCA is mainly expressed in lymphoid tissues, FANCC binding, Phosphorylation of FANC (Fanconi anemia complementation group) proteins is thought to be important for the function of the FA pathway, The FA proteins lack sequence homologies or motifs that could point to a molecular function, The amino-terminal region of the FANCA protein is required for FANCG binding, The cellular accumulation of FA proteins, The human FANCA gene maps to chromosome 16q24, a subunit of the SWI/SNF complex which remodels chromatin structure through a DNA-dependent ATPase activity, also known as FACA and FANCH, associates with the Brm-related gene 1 (BRG1) product, birth defects and chromosomal instability, including FANCA and FANCG, is subject to regulation by TNF alpha signaling, nuclear localization and functional activity of the complex, testis and ovary, 3 and encodes a 1, 455 amino acid protein, Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	FA, FA 1, FA H, FA1, FAA, FACA, FAH, FANCA_HUMAN, FANCH, Fanca, Fanconi anemia complementation group A, Fanconi anemia complementation group H, Fanconi anemia group A protein, Fanconi anemia type 1, MGC75158, Protein FACA, p-FANCA phospho S1149, FANCA phospho S1149
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	FANCA (Ser1149)
Short name	FANCA (Ser1149) Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	complementation family A (Ser1149) (Antibody to), Fanconi anemia
Alternative technique	antibodies
Alternative to gene target	FA and FA-H and FA1 and FAA and FACA and FAH and FANCH, FANCA and IDBG-48213 and ENSG00000187741 and 2175, FANCA and IDBG-630970 and ENSBTAG00000001906 and, Fanca and IDBG-198733 and ENSMUSG00000032815 and 14087, complementation group A, nuclei, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006281 and DNA repair and biological process this GO :0006461 and protein complex assembly and biological process this GO :0007140 and male meiosis and biological process this GO :0008584 and male this GO nad development and biological process this GO :0008585 and female this GO nad development and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0043240 and Fanconi anaemia nuclear complex and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding, Fanconi anemia
Identity	3582
Gene	FANCA
Long gene name	Fanconi anemia complementation group A
Synonyms gene	FACA FANCH
Synonyms	FAA FA-H FAH
Locus	16q24, 3
Discovery year	1995-12-22
GenBank acession	Z83067
Entrez gene record	2175
Pubmed identfication	7581462 9382107
Classification	Fanconi anemia complementation groups
Havana BLAST/BLAT	OTTHUMG00000173049
Locus Specific Databases	Fanconi Anaemia Mutation Database Fanconi anemia database LRG_495

FANCA (Ser1149) Antibody

FANCA (Ser1149) Antibody size: 0.1ml 281

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