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FANCC Antibody, HRP Conjugated

FANCC Antibody, HRP Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name HRP Conjugated, FANCC Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationHRP Conjugated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFANCC
SpecificityThis is a highly specific antibody against FANCC
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FANCC
Gene ID number2176
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4, Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, FANCC is expressed in a cell cycle-dependent manner, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8), In addition, In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7, The FA Group C complementation group gene encodes the protein FANCC, The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3), These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8), birth defects and chromsomal instability (1, which is a transcriptional repressor (6), which is located in both cytoplasmic and nuclear compartments, which suggests that FANCC indirectly suppresses the activity of PKR, with the lowest levels at the G1/S boundary and the highest levels in the M-phase, 2), 5), 8), Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FAC FA3
Properties Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase 
Gene targetFANCC Conjugated
Short name Conjugated, FANCC Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelHRP
Alternative name complementation family C (Antibody to), horseradish peroxidase coupled, Fanconi anemia
Alternative techniqueantibodies
Alternative to gene target FA3 and FAC and FACC, FANCC and IDBG-636496 and ENSBTAG00000017195 and 281762, FANCC and IDBG-77041 and ENSG00000158169 and 2176, Fancc and IDBG-160833 and ENSMUSG00000021461 and 14088, complementation group C, nuclei, protein binding, this GO :0002262 and myeloid cell homeostasis and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006281 and DNA repair and biological process this GO :0006289 and nucleotide-excision repair and biological process this GO :0006461 and protein complex assembly and biological process this GO :0007276 and gamete generation and biological process this GO :0007281 and germ cell development and biological process this GO :0019430 and removal of superoxide radicals and biological process this GO :0043240 and Fanconi anaemia nuclear complex and cellular component this GO :0045087 and innate immune response and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, Fanconi anemia
Identity 3584
Gene FANCC
Long gene name Fanconi anemia complementation group C
Synonyms gene FACC
Locus 9q22, 32
Discovery year 1992-11-25
GenBank acession BC006303
Entrez gene record 2176
Pubmed identfication 1303234
RefSeq identity NM_000136
Classification Fanconi anemia complementation groups
Havana BLAST/BLAT OTTHUMG00000020279
Locus Specific Databases Fanconi Anaemia Mutation Database Fanconi anemia database LRG_497

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