Name : FANCD2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4686077008
| Long name | FANCD2 Primary Polyclonal Antibody |
| Also known as | FANCD2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | FANCD2 |
| Specificity | This is a highly specific antibody against FANCD2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FANCD2 |
| Gene ID number | 2177 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation, and cellular hypersensitivity to mitomycin C (MMC), progressive bone marrow failure, targeting nuclear foci containing the BRCA 1 protein, DNA damage activates the monoubiquitination of FANC D2, Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | FA D2, FA4, FAC D2, FACD, FACD 2, FACD2, FACD2_HUMAN, FAD, FAD2, FANC D2, FANCD, FANCD 2, Fanconi anemia group D2 protein, Protein FACD2, Protein FACD2, Type 4 Fanconi pancytopenia, FA 4 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FANCD2 |
| Short name | FANCD2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | complementation family D2 (Antibody to), Fanconi anemia |
| Alternative technique | antibodies |
| Alternative to gene target | DNA polymerase binding, FA-D2 and FA4 and FACD and FAD and FAD2 and FANCD, FANCD2 and IDBG-17539 and ENSG00000144554 and 2177, FANCD2 and IDBG-644629 and ENSBTAG00000010077 and 515845, Fancd2 and IDBG-177677 and ENSMUSG00000034023 and 211651, complementation group D2, nuclei, this GO :0000793 and condensed chromosome and cellular component this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006281 and DNA repair and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007129 and synapsis and biological process this GO :0007276 and gamete generation and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0070182 and DNA polymerase binding and molecular function, this GO :0005488: binding, this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0070182: DNA polymerase binding, this GO :0005515: protein binding, this GO :0070182: DNA polymerase binding, Fanconi anemia |
| Identity | 3585 |
| Gene | FANCD2 |
| Long gene name | Fanconi anemia complementation group D2 |
| Synonyms gene | FACD FANCD |
| Synonyms | FAD FA-D2 |
| Locus | 3p25, 3 |
| Discovery year | 1996-01-04 |
| GenBank acession | AF340183 |
| Entrez gene record | 2177 |
| Pubmed identfication | 7581463 11239453 18475298 |
| Classification | Fanconi anemia complementation groups |
| Havana BLAST/BLAT | OTTHUMG00000128670 |
| Locus Specific Databases | Fanconi Anaemia Mutation Database Fanconi anemia database LRG_306 |