Name : FANCD2 Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4430707121
| Long name | ALEXA FLUOR 555 Conjugated, FANCD2 Polyclonal Antibody |
| Also known as | Anti-FANCD2 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FANCD2 |
| Specificity | This is a highly specific antibody against FANCD2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FANCD2 |
| Gene ID Number | 2177 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation, and cellular hypersensitivity to mitomycin C (MMC), progressive bone marrow failure, targeting nuclear foci containing the BRCA 1 protein, DNA damage activates the monoubiquitination of FANC D2, Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | FAD FA-D2 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | FANCD2 |
| Short name | FANCD2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, complementation family D2 (Antibody to), Fanconi anemia |
| Alternative technique | antibodies |
| Alternative to gene target | DNA polymerase binding, FA-D2 and FA4 and FACD and FAD and FAD2 and FANCD, FANCD2 and IDBG-17539 and ENSG00000144554 and 2177, FANCD2 and IDBG-644629 and ENSBTAG00000010077 and 515845, Fancd2 and IDBG-177677 and ENSMUSG00000034023 and 211651, complementation group D2, nuclei, this GO :0000793 and condensed chromosome and cellular component this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006281 and DNA repair and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007129 and synapsis and biological process this GO :0007276 and gamete generation and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0070182 and DNA polymerase binding and molecular function, this GO :0005488: binding, this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0070182: DNA polymerase binding, this GO :0005515: protein binding, this GO :0070182: DNA polymerase binding, Fanconi anemia |
| Identity | 3585 |
| Gene | FANCD2 |
| Long gene name | Fanconi anemia complementation group D2 |
| Synonyms gene | FACD FANCD |
| Locus | 3p25, 3 |
| Discovery year | 1996-01-04 |
| GenBank acession | AF340183 |
| Entrez gene record | 2177 |
| Pubmed identfication | 7581463 11239453 18475298 |
| Classification | Fanconi anemia complementation groups |
| Havana BLAST/BLAT | OTTHUMG00000128670 |
| Locus Specific Databases | Fanconi Anaemia Mutation Database Fanconi anemia database LRG_306 |