Name : FANCD2 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9426418414
| Long name | Biotin Conjugated, FANCD2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FANCD2 |
| Specificity | This is a highly specific antibody against FANCD2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human FANCD2 |
| Gene ID number | 2177 |
| Tested applications | IHC-P |
| Recommended dilutions | IHC-P(1:100-500) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation, and cellular hypersensitivity to mitomycin C (MMC), progressive bone marrow failure, targeting nuclear foci containing the BRCA 1 protein, DNA damage activates the monoubiquitination of FANC D2, Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | FAD FA-D2 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FANCD2 Conjugated |
| Short name | Conjugated, FANCD2 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, complementation family D2 (Antibody to), Fanconi anemia |
| Alternative technique | antibodies |
| Alternative to gene target | DNA polymerase binding, FA-D2 and FA4 and FACD and FAD and FAD2 and FANCD, FANCD2 and IDBG-17539 and ENSG00000144554 and 2177, FANCD2 and IDBG-644629 and ENSBTAG00000010077 and 515845, Fancd2 and IDBG-177677 and ENSMUSG00000034023 and 211651, complementation group D2, nuclei, this GO :0000793 and condensed chromosome and cellular component this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006281 and DNA repair and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007129 and synapsis and biological process this GO :0007276 and gamete generation and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0070182 and DNA polymerase binding and molecular function, this GO :0005488: binding, this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0070182: DNA polymerase binding, this GO :0005515: protein binding, this GO :0070182: DNA polymerase binding, Fanconi anemia |
| Identity | 3585 |
| Gene | FANCD2 |
| Long gene name | Fanconi anemia complementation group D2 |
| Synonyms gene | FACD FANCD |
| Locus | 3p25, 3 |
| Discovery year | 1996-01-04 |
| GenBank acession | AF340183 |
| Entrez gene record | 2177 |
| Pubmed identfication | 7581463 11239453 18475298 |
| Classification | Fanconi anemia complementation groups |
| Havana BLAST/BLAT | OTTHUMG00000128670 |
| Locus Specific Databases | Fanconi Anaemia Mutation Database Fanconi anemia database LRG_306 |