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FANCD2 Antibody, Biotin Conjugated

FANCD2 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, FANCD2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFANCD2
SpecificityThis is a highly specific antibody against FANCD2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FANCD2
Gene ID number2177
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation, and cellular hypersensitivity to mitomycin C (MMC), progressive bone marrow failure, targeting nuclear foci containing the BRCA 1 protein, DNA damage activates the monoubiquitination of FANC D2, Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FAD FA-D2
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFANCD2 Conjugated
Short name Conjugated, FANCD2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, complementation family D2 (Antibody to), Fanconi anemia
Alternative techniqueantibodies
Alternative to gene target DNA polymerase binding, FA-D2 and FA4 and FACD and FAD and FAD2 and FANCD, FANCD2 and IDBG-17539 and ENSG00000144554 and 2177, FANCD2 and IDBG-644629 and ENSBTAG00000010077 and 515845, Fancd2 and IDBG-177677 and ENSMUSG00000034023 and 211651, complementation group D2, nuclei, this GO :0000793 and condensed chromosome and cellular component this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006281 and DNA repair and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007129 and synapsis and biological process this GO :0007276 and gamete generation and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0070182 and DNA polymerase binding and molecular function, this GO :0005488: binding, this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0070182: DNA polymerase binding, this GO :0005515: protein binding, this GO :0070182: DNA polymerase binding, Fanconi anemia
Identity 3585
Gene FANCD2
Long gene name Fanconi anemia complementation group D2
Synonyms gene FACD FANCD
Locus 3p25, 3
Discovery year 1996-01-04
GenBank acession AF340183
Entrez gene record 2177
Pubmed identfication 7581463 11239453 18475298
Classification Fanconi anemia complementation groups
Havana BLAST/BLAT OTTHUMG00000128670
Locus Specific Databases Fanconi Anaemia Mutation Database Fanconi anemia database LRG_306

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