Filters

FANCM Antibody, Biotin Conjugated

FANCM Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, FANCM Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFANCM
SpecificityThis is a highly specific antibody against FANCM
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FANCM
Gene ID number57697
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background At the cellular level, Eight of these proteins, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL and FANCM, FANCM (Fanconi anemia, FANCM is phosphorylated in a cell cycle-dependent manner and is believed to function as an anchor, Localizing to chromatin fractions, Mutations in the gene encoding FANCM can lead to Fanconi anemia, The thirteen FA proteins that have been characterized are important for regulating chromosomal stability and genome surveillance, birth defects and chromosomal instability, complementation group M) is a member of the DEAD-box helicase family of proteins and contains a DEAH helicase domain and a nuclease domain, comprise the FA core complex, namely FANCA, recruiting the FA core complex to chromatin, which catalyzes a key reaction in DNA repair: the monoubiquitination of FANCD2, Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FAAP250
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFANCM Conjugated
Short name Conjugated, FANCM Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, complementation family M (Antibody to), Fanconi anemia
Alternative techniqueantibodies
Alternative to gene target FANCM and IDBG-5587 and ENSG00000187790 and 57697, Fancm and IDBG-143248 and ENSMUSG00000055884 and 104806, complementation group M, hydrolase activity, nuclei, this GO :0000712 and resolution of meiotic recombination intermediates and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0004386 and helicase activity and molecular function this GO :0004518 and nuclease activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0006259 and DNA metabolic process and biological process this GO :0006281 and DNA repair and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0031297 and replication fork processing and biological process this GO :0043240 and Fanconi anaemia nuclear complex and cellular component this GO :0071821 and FANCM-MHF complex and cellular component this GO :0090305 and nucleic acid phosphodiester bond hydrolysis and biological process, this GO :0003676: nucleic acid binding, this GO :0003676: nucleic acid binding and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0004386: helicase activity and also this GO :0004518: nuclease activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016787: hydrolase activity, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0004386: helicase activity, this GO :0004518: nuclease activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016787: hydrolase activity, Fanconi anemia
Identity 23168
Gene FANCM
Long gene name Fanconi anemia complementation group M
Synonyms gene KIAA1596
Synonyms gene name KIAA1596
Locus 14q21, 2
Discovery year 2003-11-21
GenBank acession AK001672
Entrez gene record 57697
Pubmed identfication 10997877 16116422
RefSeq identity XM_048128
Classification RNA helicases Fanconi anemia complementation groups
Havana BLAST/BLAT OTTHUMG00000170807
Locus Specific Databases Fanconi anemia database LRG_502

Similar products

Subscribe to our Newsletter