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FAS Antibody

FAS Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenFAS
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, WB
Recommended dilutionsImmunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the FAS antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis FAS antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P25445
PurityAntigen affinity
Description It has been shown to play a central role in the physiological regulation of programmed cell death, MAPK3/ERK1, The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), This receptor contains a death domain, This receptor has been also shown to activate NF-kappaB, and MAPK8/JNK, and caspase 10, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells, and leads to apoptosis, caspase 8, FAS is a member of the TNF-receptor superfamily
ImmunogenA portion of amino acids 185-211 from the human protein was used as the immunogen for this FAS antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the FAS antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetFAS
Short nameFAS Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name member 6) (Antibody to), Fas (TNF receptor superfamily
Alternative techniqueantibodies
Alternative to gene target ALPS1A and APO-1 and APT1 and CD95 and FAS1 and FASTM and TNFRSF6, FAS and IDBG-637356 and ENSBTAG00000010785 and 282488, FAS and IDBG-81669 and ENSG00000026103 and 355, Fas and IDBG-159577 and ENSMUSG00000024778 and 14102, identical protein binding, member 6), nuclei, this GO :0002377 and immunoglobulin production and biological process this GO :0003014 and renal system process and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006924 and activation-induced cell death of T cells and biological process this GO :0006925 and inflammatory cell apoptotic process and biological process this GO :0006927 and transformed cell apoptotic process and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007623 and circadian rhythm and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0009636 and response to toxic substance and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010467 and gene expression and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0019724 and B cell mediated immunity and biological process this GO :0019900 and kinase binding and molecular function this GO :0031264 and death-inducing signaling complex and cellular component this GO :0031265 and CD95 death-inducing signaling complex and cellular component this GO :0032464 and positive regulation of protein homooli this GO merization and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043029 and T cell homeostasis and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0045121 and membrane raft and cellular component this GO :0045619 and regulation of lymphocyte differentiation and biological process this GO :0045637 and regulation of myeloid cell differentiation and biological process this GO :0048536 and spleen development and biological process this GO :0050869 and negative regulation of B cell activation and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071285 and cellular response to lithium ion and biological process this GO :0071455 and cellular response to hyperoxia and biological process this GO :0097049 and motor neuron apoptotic process and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :0097527 and necroptotic signaling pathway and biological process this GO :2001239 and regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :2001241 and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0004871: signal transducer activity, this GO :0004871: signal transducer activity and also this GO :0004872: receptor activity and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005515: protein binding and also this GO :0019900: kinase binding and also this GO :0042802: identical protein binding, this GO :0004872: receptor activity, this GO :0004888: transmembrane signaling receptor activity, this GO :0005515: protein binding, this GO :0019900: kinase binding, this GO :0042802: identical protein binding, Fas (TNF receptor superfamily
Identity 3594
Gene FASN
Long gene name fatty acid synthase
Synonyms FAS SDR27X1
Synonyms name member 1 , short chain dehydrogenase/reductase family 27X
Locus 17q25, 3
Discovery year 1994-05-17
GenBank acession U26644
Entrez gene record 2194
Pubmed identfication 7835891 7567999 19027726
RefSeq identity NM_004104
Classification Short chain dehydrogenase/reductase superfamily
Havana BLAST/BLAT OTTHUMG00000178527

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