| Long name | Fas Ligand Primary Polyclonal Antibody |
| Also known as | Fas Ligand PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Fas Ligand |
| Specificity | This is a highly specific antibody against Fas Ligand |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 170-220/281 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fas Ligand |
| Gene ID number | 356 |
| Swiss Prot | P48023 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects, May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development, TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition, a receptor that transduces the apoptotic signal into cells, in the antigen-stimulated suicide of mature T-cells, or both, Cytokine that binds to TNFRSF6/FAS |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ALPS1B, APT1LG1, Apoptosis antigen ligand, CD178, CD95 ligand, CD95-L, CD95L, FASL, FASLG, Fas antigen ligand, Fas ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6, APTL |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Description | Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling |
| Gene target | Fas Ligand |
| Short name | Fas Ligand Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | member 6) Ligand (Antibody to), Fas (TNF receptor superfamily |
| Alternative technique | antibodies |
| Identity | 11936 |
| Gene | FASLG |
| Long gene name | Fas ligand |
| Synonyms gene | APT1LG1 TNFSF6 |
| Synonyms gene name | member 6 Fas ligand (TNF superfamily, member 6) , tumor necrosis factor (ligand) superfamily |
| Synonyms | FasL CD178 |
| Locus | 1q24, 3 |
| Discovery year | 1994-12-09 |
| GenBank acession | U11821 |
| Entrez gene record | 356 |
| Pubmed identfication | 7826947 9022072 |
| Classification | Endogenous ligands Tumor necrosis factor superfamily CD molecules Death inducing signaling complex |
| Havana BLAST/BLAT | OTTHUMG00000034841 |
| Locus Specific Databases | FASLGbase: Mutation registry for Autoimmune lymphoproliferative syndrome, type 1B (ALPS1B) (previously known as TNFSF6base) LRG_58 |
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