Filters

Fas Ligand Antibody, ALEXA FLUOR 488

Fas Ligand Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Fas Ligand Polyclonal Antibody
Also known asAnti-Fas Ligand PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFas Ligand
SpecificityThis is a highly specific antibody against Fas Ligand
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range170-220/281
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fas Ligand
Gene ID Number356
Swiss ProtP48023
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects, May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development, TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition, a receptor that transduces the apoptotic signal into cells, in the antigen-stimulated suicide of mature T-cells, or both, Cytokine that binds to TNFRSF6/FAS
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms FasL CD178
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Fas Ligand Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Description Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling
Gene targetFas Ligand
Short nameFas Ligand Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, member 6) Ligand (Antibody to), Fas (TNF receptor superfamily
Alternative techniqueantibodies
Identity 11936
Gene FASLG
Long gene name Fas ligand
Synonyms gene APT1LG1 TNFSF6
Synonyms gene name member 6 Fas ligand (TNF superfamily, member 6) , tumor necrosis factor (ligand) superfamily
Locus 1q24, 3
Discovery year 1994-12-09
GenBank acession U11821
Entrez gene record 356
Pubmed identfication 7826947 9022072
Classification Endogenous ligands Tumor necrosis factor superfamily CD molecules Death inducing signaling complex
Havana BLAST/BLAT OTTHUMG00000034841
Locus Specific Databases FASLGbase: Mutation registry for Autoimmune lymphoproliferative syndrome, type 1B (ALPS1B) (previously known as TNFSF6base) LRG_58

Similar products

Subscribe to our Newsletter