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FASN Antibody

FASN Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenFASN
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IHC, WB, IF
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:200, Western blot: 1:1000
NotesTitration of the FASN antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis FASN antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P49327
PurityPurified
Description In some cancer cell lines, Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha, into long-chain saturated fatty acids, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), FASN (Fatty acid synthase) is a multifunctional protein
ImmunogenA portion of amino acids 942-973 from human Fatty acid synthase was used as the immunogen for this FASN antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the FASN antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetFASN
Short nameFASN Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFASN (Antibody to)
Alternative techniqueantibodies
Identity 3594
Gene FASN
Long gene name fatty acid synthase
Synonyms FAS SDR27X1
Synonyms name member 1 , short chain dehydrogenase/reductase family 27X
Locus 17q25, 3
Discovery year 1994-05-17
GenBank acession U26644
Entrez gene record 2194
Pubmed identfication 7835891 7567999 19027726
RefSeq identity NM_004104
Classification Short chain dehydrogenase/reductase superfamily
Havana BLAST/BLAT OTTHUMG00000178527

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