Name : FASN Antibody / Fatty acid synthase
Supplier : NJS POLY
Price :406
SKU : GEN8920474128
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | FASN / Fatty acid synthase |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Optimal dilution of the FASN antibody should be determined by the researcher |
| Intented use | This FASN antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P49327 |
| Purity | Antigen affinity |
| Description | In some cancer cell lines, Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, The enzyme encoded by this gene is a multifunctional protein, in the presence of NADPH, in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha, into long-chain saturated fatty acids, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene |
| Immunogen | Amino acids 1-226 of human FASN were used as the immunogen for the FASN antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the FASN antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | Cytoplasmic |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | FASN / Fatty acid synthase |
| Short name | FASN Antibody / Fatty acid synthase |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | FASN (Antibody to) / Fatty acid synthase |
| Alternative technique | antibodies |
| Identity | 3594 |
| Gene | FASN |
| Long gene name | fatty acid synthase |
| Synonyms | FAS SDR27X1 |
| Synonyms name | member 1 , short chain dehydrogenase/reductase family 27X |
| Locus | 17q25, 3 |
| Discovery year | 1994-05-17 |
| GenBank acession | U26644 |
| Entrez gene record | 2194 |
| Pubmed identfication | 7835891 7567999 19027726 |
| RefSeq identity | NM_004104 |
| Classification | Short chain dehydrogenase/reductase superfamily |
| Havana BLAST/BLAT | OTTHUMG00000178527 |