Name : FBXL21 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN1882357475
| Long name | Biotin Conjugated, FBXL21 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FBXL21 |
| Specificity | This is a highly specific antibody against FBXL21 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human FBXL21/FBL3B |
| Gene ID number | 26223 |
| Tested applications | IHC-P |
| Recommended dilutions | IHC-P(1:100-500) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, F-box proteins are members of a large family that regulates cell cycle, FBL3B also contains three LRR (leucine-rich) repeats, FBL3B contains one 40 amino acid F-box region, FBL3B is a substrate-recognition component of the SCF complex that interacts with Skp1 p19 and CUL-1, FBL3B is also associated with expression and regulation of circadian and cryptochrome proteins, IkB-a and b-catenin, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, immune response, making it a member of the F-box family, signaling cascades and developmental programs by targeting proteins, such as cyclins, FBL3B is a 434 amino acid protein encoded by the human gene FBXL21 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | FBL3B Fbl21 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FBXL21 Conjugated |
| Short name | Conjugated, FBXL21 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, FBXL21 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13600 |
| Gene | FBXL21 |
| Long gene name | F-box and leucine rich repeat protein 21 (gene/pseudogene) |
| Synonyms gene | FBXL3B FBXL3P |
| Synonyms gene name | F-box and leucine-rich repeat protein 3 pseudogene F-box and leucine-rich repeat protein 21 F-box and leucine-rich repeat protein 21 (gene/pseudogene) |
| Locus | 5q31, 1 |
| Discovery year | 2000-09-27 |
| GenBank acession | AF129533 |
| Entrez gene record | 26223 |
| Pubmed identfication | 10531035 |
| RefSeq identity | NM_012159 |
| Classification | F-box and leucine rich repeat proteins |
| Havana BLAST/BLAT | OTTHUMG00000155971 |