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FBXO11 Antibody, ALEXA FLUOR 350

FBXO11 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, FBXO11 Polyclonal Antibody
Also known asAnti-FBXO11 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFBXO11
SpecificityThis is a highly specific antibody against FBXO11
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range85-127/927
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FBXO11
Gene ID Number80204
Swiss ProtQ86XK2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen BCL6 and PRDM1/BLIMP1, Binds to and neddylates phosphorylated p53/TP53, SCF(FBXO11) does not seem to direct ubiquitination of p53/TP53, The SCF(FBXO11) complex also mediates ubiquitination and degradation of DTL, The SCF(FBXO11) complex mediates ubiquitination and degradation of BCL6, an important step for the regulation of TGF-beta signaling, cell migration and the timing of the cell-cycle progression and exit, inhibiting its transcriptional activity, such as DTL/CDT2, thereby playing a role in the germinal center B-cells terminal differentiation toward memory B-cells and plasma cells, Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms FBX11 UBR6
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetFBXO11
Short nameFBXO11 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, FBXO11 (Antibody to)
Alternative techniqueantibodies
Identity 13590
Gene FBXO11
Long gene name F-box protein 11
Synonyms gene name F-box only protein 11
Synonyms name ubiquitin protein ligase E3 component n-recognin 6
Locus 2p16, 3
Discovery year 2000-09-27
GenBank acession AF174599
Entrez gene record 80204
Pubmed identfication 10531035 16487488 18162545
RefSeq identity NM_012167 NM_018693 NM_025133
Classification F-boxes other Ubiquitin protein ligase E3 component n-recognins
Havana BLAST/BLAT OTTHUMG00000129130

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