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FBXO11 Antibody, Cy5.5 Conjugated

FBXO11 Antibody, Cy5.5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, FBXO11 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFBXO11
SpecificityThis is a highly specific antibody against FBXO11
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range85-127/927
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human FBXO11
Gene ID number80204
Swiss ProtQ86XK2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BCL6 and PRDM1/BLIMP1, Binds to and neddylates phosphorylated p53/TP53, SCF(FBXO11) does not seem to direct ubiquitination of p53/TP53, The SCF(FBXO11) complex also mediates ubiquitination and degradation of DTL, The SCF(FBXO11) complex mediates ubiquitination and degradation of BCL6, an important step for the regulation of TGF-beta signaling, cell migration and the timing of the cell-cycle progression and exit, inhibiting its transcriptional activity, such as DTL/CDT2, thereby playing a role in the germinal center B-cells terminal differentiation toward memory B-cells and plasma cells, Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms FBX11 UBR6
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetFBXO11 Conjugated
Short name Conjugated, FBXO11 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, FBXO11 (Antibody to)
Alternative techniqueantibodies
Identity 13590
Gene FBXO11
Long gene name F-box protein 11
Synonyms gene name F-box only protein 11
Synonyms name ubiquitin protein ligase E3 component n-recognin 6
Locus 2p16, 3
Discovery year 2000-09-27
GenBank acession AF174599
Entrez gene record 80204
Pubmed identfication 10531035 16487488 18162545
RefSeq identity NM_012167 NM_018693 NM_025133
Classification F-boxes other Ubiquitin protein ligase E3 component n-recognins
Havana BLAST/BLAT OTTHUMG00000129130

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