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FBXO25 Antibody

FBXO25 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFBXO25 Primary Polyclonal Antibody
Also known asFBXO25 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFBXO25
SpecificityThis is a highly specific antibody against FBXO25
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FBXO25
Gene ID number26260
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Disruption of the gene encoding FBXO25 can lead to X-linked mental retardation, Expressed at high levels in brain, F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, FBXO25 belongs to the Fbxs class, FBXO25 localizes predominantly to the nucleus and directly interacts with Skp1 p19 and CUL-1, Fbls containing leucine rich repeats, IkB-a and b-catenin, The F box proteins are divided into 3 classes: Fbws containing WD 40 domains, The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box), There are three named isoforms produced by alternative splicing, They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, also known as FBX25, and Fbxs containing either different protein protein interaction modules or no recognizable motifs, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, immune response, is a 367 amino acid protein that contains one C-terminal F-box domain and belongs to the Fbx class of the F-box family of proteins, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, the F box, which function in phosphorylation dependent ubiquitination, FBXO25, FBXO25 is a member of the F box protein family which is characterized by an approximately 40 amino acid motif
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names F box protein 25, F box protein Fbx25, F-box only protein 25, FBX25, MGC20256, MGC51975, OTTHUMP00000115399, F box only protein 25
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFBXO25
Short nameFBXO25 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFBXO25 (Antibody to)
Alternative techniqueantibodies
Identity 13596
Gene FBXO25
Long gene name F-box protein 25
Synonyms gene name F-box only protein 25
Synonyms FBX25
Locus 8p23, 3
Discovery year 2000-09-27
GenBank acession AF174605
Entrez gene record 26260
Pubmed identfication 10531035 10531037
RefSeq identity NM_012173
Classification F-boxes other
Havana BLAST/BLAT OTTHUMG00000090341

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