Name : FBXO25 Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6352008060
| Long name | ALEXA FLUOR 555 Conjugated, FBXO25 Polyclonal Antibody |
| Also known as | Anti-FBXO25 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FBXO25 |
| Specificity | This is a highly specific antibody against FBXO25 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FBXO25 |
| Gene ID Number | 26260 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Disruption of the gene encoding FBXO25 can lead to X-linked mental retardation, Expressed at high levels in brain, F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, FBXO25 belongs to the Fbxs class, FBXO25 localizes predominantly to the nucleus and directly interacts with Skp1 p19 and CUL-1, Fbls containing leucine rich repeats, IkB-a and b-catenin, The F box proteins are divided into 3 classes: Fbws containing WD 40 domains, The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box), There are three named isoforms produced by alternative splicing, They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, also known as FBX25, and Fbxs containing either different protein protein interaction modules or no recognizable motifs, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, immune response, is a 367 amino acid protein that contains one C-terminal F-box domain and belongs to the Fbx class of the F-box family of proteins, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, the F box, which function in phosphorylation dependent ubiquitination, FBXO25, FBXO25 is a member of the F box protein family which is characterized by an approximately 40 amino acid motif |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | FBX25 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | FBXO25 |
| Short name | FBXO25 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, FBXO25 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13596 |
| Gene | FBXO25 |
| Long gene name | F-box protein 25 |
| Synonyms gene name | F-box only protein 25 |
| Locus | 8p23, 3 |
| Discovery year | 2000-09-27 |
| GenBank acession | AF174605 |
| Entrez gene record | 26260 |
| Pubmed identfication | 10531035 10531037 |
| RefSeq identity | NM_012173 |
| Classification | F-boxes other |
| Havana BLAST/BLAT | OTTHUMG00000090341 |