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FBXO25 Antibody, FITC Conjugated

FBXO25 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, FBXO25 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFBXO25
SpecificityThis is a highly specific antibody against FBXO25
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FBXO25
Gene ID number26260
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Disruption of the gene encoding FBXO25 can lead to X-linked mental retardation, Expressed at high levels in brain, F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, FBXO25 belongs to the Fbxs class, FBXO25 localizes predominantly to the nucleus and directly interacts with Skp1 p19 and CUL-1, Fbls containing leucine rich repeats, IkB-a and b-catenin, The F box proteins are divided into 3 classes: Fbws containing WD 40 domains, The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box), There are three named isoforms produced by alternative splicing, They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, also known as FBX25, and Fbxs containing either different protein protein interaction modules or no recognizable motifs, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, immune response, is a 367 amino acid protein that contains one C-terminal F-box domain and belongs to the Fbx class of the F-box family of proteins, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, the F box, which function in phosphorylation dependent ubiquitination, FBXO25, FBXO25 is a member of the F box protein family which is characterized by an approximately 40 amino acid motif
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FBX25
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFBXO25 Conjugated
Short name FITC Conjugated, FBXO25 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, FBXO25 (Antibody to)
Alternative techniqueantibodies
Identity 13596
Gene FBXO25
Long gene name F-box protein 25
Synonyms gene name F-box only protein 25
Locus 8p23, 3
Discovery year 2000-09-27
GenBank acession AF174605
Entrez gene record 26260
Pubmed identfication 10531035 10531037
RefSeq identity NM_012173
Classification F-boxes other
Havana BLAST/BLAT OTTHUMG00000090341

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