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FBXW12 Antibody, Biotin Conjugated

FBXW12 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, FBXW12 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFBXW12
SpecificityThis is a highly specific antibody against FBXW12
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FBXW12/FBXO35
Gene ID number285231
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, FBXO35 (F-box only protein 35), FBXO35 can directly interact with Skp1 p19 and CUL-1, FBXO35 is ubiquitously expressed at low levels in most human tissues, I&, They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, They function by targeting proteins, Via its F-box domain, also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), and â, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, including the cell cycle, is a 464 amino acid protein that contains one C-terminal F-box domain, signaling cascades and developmental processes, such as cyclins, the immune response, #730, &circ, «, -catenin, B-&, Belonging to the F-box family of proteins, aring
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms Fbw12
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFBXW12 Conjugated
Short name Conjugated, FBXW12 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, FBXW12 (Antibody to)
Alternative techniqueantibodies
Identity 20729
Gene FBXW12
Long gene name F-box and WD repeat domain containing 12
Synonyms gene FBXO35
Synonyms gene name F-box only protein 35 F-box and WD-40 domain protein 12
Locus 3p21, 31
Discovery year 2003-04-04
GenBank acession AK097594 AY247969
Entrez gene record 285231
Pubmed identfication 15040455
RefSeq identity NM_207102
Classification F-box and WD repeat domain containing WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000133530

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