Name : FBXW12 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN7919428104
| Long name | Biotin Conjugated, FBXW12 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FBXW12 |
| Specificity | This is a highly specific antibody against FBXW12 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human FBXW12/FBXO35 |
| Gene ID number | 285231 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, FBXO35 (F-box only protein 35), FBXO35 can directly interact with Skp1 p19 and CUL-1, FBXO35 is ubiquitously expressed at low levels in most human tissues, I&, They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, They function by targeting proteins, Via its F-box domain, also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), and â, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, including the cell cycle, is a 464 amino acid protein that contains one C-terminal F-box domain, signaling cascades and developmental processes, such as cyclins, the immune response, #730, &circ, «, -catenin, B-&, Belonging to the F-box family of proteins, aring |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | Fbw12 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FBXW12 Conjugated |
| Short name | Conjugated, FBXW12 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, FBXW12 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 20729 |
| Gene | FBXW12 |
| Long gene name | F-box and WD repeat domain containing 12 |
| Synonyms gene | FBXO35 |
| Synonyms gene name | F-box only protein 35 F-box and WD-40 domain protein 12 |
| Locus | 3p21, 31 |
| Discovery year | 2003-04-04 |
| GenBank acession | AK097594 AY247969 |
| Entrez gene record | 285231 |
| Pubmed identfication | 15040455 |
| RefSeq identity | NM_207102 |
| Classification | F-box and WD repeat domain containing WD repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000133530 |